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右美托咪啶与小儿癫外科

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摘要 外科手术是小儿难治性癫的重要治疗手段,年龄已不再是手术的禁忌,这也对麻醉提出更高的要求。小儿无法配合术前检查,麻醉需要围术期全程介入,癫的特点要求在保证麻醉深度的同时,不能影响癫异常放电的观察。当前常用的镇静和全身麻醉药物对呼吸、循环干扰大,且随剂量增大明显抑制全脑放电,故都不是小儿癫疒间手术的理想药物。右美托咪啶作用于α2肾上腺素能受体,抑制突触后去甲肾上腺素释放,起镇静、镇痛作用,其对呼吸、循环干扰小,既不激发也不抑制癫疒间灶异常放电,是较为理想的小儿癫手术麻醉用药。本文就右美托咪啶在小儿癫外科的应用进展作一综述。
作者 孙梅 施冲
出处 《中国微侵袭神经外科杂志》 CAS 2013年第11期525-528,共4页 Chinese Journal of Minimally Invasive Neurosurgery
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参考文献23

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