期刊文献+

小剂量硼替佐米联合T-VAD方案治疗老年多发性骨髓瘤八例报告 被引量:1

原文传递
导出
摘要 多发性骨髓瘤(multiple myeloma,MM)呈逐年增高趋势。临床上治疗〉70岁患者仍是一个难题,因为随着年龄的增长,各重要脏器功能逐渐下降,并常伴有其他基础疾病,个体情况差异较大,对药物治疗耐受性差,更需不断探讨有效的个体化方案。本研究采用小剂量硼替佐米联合T-VAD方案治疗〉70岁初诊MM患者8例。
出处 《中华肿瘤防治杂志》 CAS 北大核心 2013年第21期1697-1698,共2页 Chinese Journal of Cancer Prevention and Treatment
  • 相关文献

参考文献11

  • 1陈世伦,于力,邱录贵.多发性骨髓瘤诊疗常规[M].北京:人民卫生出版社,2012:61-62.
  • 2Durie BG,Harousseau JL,Miguel JS,et al. International uniform response criteria for multiple myeloma[J]. Leukemia, 2006,20 (9) : 1467-1473.
  • 3Anderson KC, A|sina M,Bensinger W,et aL NCCN clinical prac- tice guidelines in oncology multiple myeloma [J]. J Natl Compr Canc Netw,2013,11(1) :11- 17.
  • 4Mateos MV, Oriol A, MartinevL6pez J, et aL Bortezomib, melphalan, and prednisone versus bortezomib,thalidomide, and prednisone as in duction therapy followed by maintenance treatment with bortezomib and thalidomide versus bortezomib and prednisone in elderly patients with untreated multiple myeloma:a randomised trial [J]. Lancet On- col,2010,11(10) : 934-941.
  • 5Fukushima T,Nakamura T,Iwao H,et al. Efficacy and safety of bortezomib plus dexamethasone therapy for refractory or re lapsed multiple myeloma: once-weekly administration of borte- zomib may reduce the incidence of gastrointestinal adverse events [J]. Anticancer Res,2011,31(6):2297-2302.
  • 6康岩,赵月莹,郭梅,余长林,乔建辉,胡锴勋,孙琪云.减低剂量的硼替佐米治疗老年性多发性骨髓瘤临床研究[J].第二军医大学学报,2012,33(10):1142-1144. 被引量:7
  • 7苏基滢,周立宇,徐黎,宋陆茜,张曦,肖超,常春康.偏小剂量的硼替佐米联合地塞米松治疗初发多发性骨髓瘤疗效观察[J].癌症进展,2012,10(1):80-83. 被引量:9
  • 8张伟,张岩.硼替佐米治疗多发性骨髓瘤的临床观察[J].中华肿瘤防治杂志,2010,17(17):1368-1370. 被引量:9
  • 9Morabito F,Gentile M, Mazzone C, et al. Safety and efficacy of bortezomih-melphalan prednisone-thalidomide followed by borte zomib-thalidomide maintenance (VMPT-VT) versus bortezomib melphalan-prednisone(VMP) in untreated multiple myeloma pa- tients with renal impairment I-J]. Blood, 2011,118 ( 22 ) : 5759-5766.
  • 10Richardson PG,Sonneveld P,Schuster M, et al. Extended follow up of a phase 3 trial in relapsed mutiple myeloma:final time to e- vent results from the APEX trial[J]. Blood, 2007, 110(10): 3557- 3560.

二级参考文献27

  • 1吕晓芳,于世英,冷彦.骨代谢生化指标在恶性肿瘤骨转移诊断中的价值[J].中国肿瘤临床,2007,34(3):154-156. 被引量:12
  • 2刘桐宇,叶建新.蛋白酶体抑制剂治疗多药耐药肿瘤机制的研究进展[J].中华肿瘤防治杂志,2007,14(15):1187-1190. 被引量:6
  • 3Bross P F, Kane R, Farrell A T, et al. Approval summary for bortezomib for injection in the treatment of multiple myeloma [J]. Clin Cancer Res, 2004, 10(12): 3954.
  • 4Jagannath S, Richardson P G, Barlogie B, el al. Bortezomib in combination with dexamethasone for the treatment of patients with relapsed and/or refractory multiple myeloma with less than optimal response to bortezomib alone[J]. Haematologica, 2006, 91 :929-934.
  • 5Jagannath S, Durie B G, Wolf J, et aI. Bortezomib therapy alone and in combination with dexamethasone for previously un treated symptomatic multiple myeloma[J]. Br J Haematol, 2005 129(6) : 776-783.
  • 6Richardson P G, Barlogie B, Berenson N J, et al. A phase 2 study of bortezomib in relapsed,refractory myeloma[J]. N Engl J Med,2003,348 : 2609-2617.
  • 7Davies F E, Wu P, Jenner M, et al. The combination of cyclophosphamide,velcade and dexamethasone induces high response rates with comparable toxicity to velcade alone and velcade plus dexamethasone[J]. Haematologica,2007,92(8) :1149 -1150.
  • 8Evangelos T, Athanasios A, Efstathios K, et al. The combination of bortezomib, meiphalan, dexamethasone and intermittent thalidomide (VMDT) is an effective treatment for relapsed/refractory myeloma: Results of a phase clinical trial[J]. Blood, 2005, 106: 363.
  • 9Chanan-Khan A A, Miller K C, McCarthy P, et al. A phase II study of Veleade (V). Doxil (D) in combination with low dose thalidomide (T) as salvage therapy for patients with relapsed or refractory multiple myeloma (MM) and Waldenstorm macroglobulinemia (WM) : Encouraging preliminary results[J]. Blood, 2004, 104(11): 2421.
  • 10Richardson P G, Anderson K C. Multiple myeloma [ M]. London : Remedica Publishing, 2004 : 64.

共引文献31

同被引文献13

引证文献1

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部