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中国控制乙型肝炎的下一步工作:重点应放在控制围产期病毒传播 被引量:13

The next step in controlling HBV in China:Focus on preventing perinatal transmission of the virus
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摘要 乙型肝炎(乙肝)病毒感染在中国是最为严重传染病之一1。尽管自1982年已有乙肝疫苗可以有效预防,但目前中国仍约有9300万乙肝病毒(HBV)携带者,每年用于治疗乙肝的费用约1000亿元人民币(约合106亿英镑,123亿欧元,160亿美元)2。乙肝感染不仅增加了患肝癌和肝硬化的风险3,而且乙肝患者还可能在求学、工作、人际关系及家庭中受到歧视4。
出处 《英国医学杂志中文版》 2013年第5期282-283,共2页 The BMJ Chinese Edition
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参考文献12

  • 1Liu J, Fan D. Hepatitis B in China Lancet 2007 ;369: 1582-3.
  • 2News C. China annually for hepatitis B treatment costs up to 100 hillion yuan,2013. www.chinanews.com/jk/2013/01-16/4494401. shtm!.
  • 3El-Serag HB. Epidemiology of viral hepatitis and hepatocellular carcinoma. Gastroenterology 2012; 142: 1264-73e1.
  • 4Yang T, Wu MC. Discrimination against hepatitis B carriers in China. Lancet 2011 ;378: 1059.
  • 5Liang X, Bi S, Yang W , Wang L, Cui G, Cui F, et al. Epidemiological serosurvey of hepatitis B in China-declining HBV prevalence due to hepatitis B vaccination. Vaccine 2009 ;27 :6550-7.
  • 6Zou H, Chen Y, Duan Z, Zhang H, Pan C. Virologic factors associated with failure to passive-active immunoprophylaxis in infants born to HBsAg-positive mothers. J Viral Hepatitis 2012; 19: e18-25.
  • 7Dusheiko G. Interruption of mother-to-infant transmission of hepatitis B: time to include selective antiviral prophylaxis? Lancet 2012 ;379 :2019-21.
  • 8Pan CQ, Duan ZP, Bhamidimarri KR, Zou HB, Liang XF, Li J, et al. An algorithm for risk assessment and intervention of mother to child transmission of hepatitis B virus. Clin Castroenterol Hepatol 2012; 10 :452-9.
  • 9Bai GQ, Li SH, Yue YF , Shi 1. The study on role of peripheral blood mononuclear cell in HBV intrauterine infection. Arch Gynecol Obstet 2011 ;283 :317-21.
  • 10Kazim SN, Wakil SM, Khan LA, Hasnain SE, Sarin SK. Vertical transmission of hepatitis B virus despite maternal lamivudine therapy. Lancet 2002 ;359: 1488-9.

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