利培酮治疗首发精神分裂症

Risperidone in the Treatment of First-Episode Schizophrenia

为观察利培酮治疗首发精神分裂症的有效性及安全性 ,采用口服利培酮治疗 2 0例首发精神分裂症住院患者 ,疗程 8周 ,以PANSS评定疗效 ,TESS观察副反应。结果 :显效率 40 % ,有效率 75 % ,起效时间为 1周。说明利培酮能有效地治疗首发精神分裂症 ,对阳性、阴性症状都有效 ,副反应小 ,安全性高。

To investigate the efficacy and safety of risperidone in the treatment of first-episode schizophrenia. 20 first-episode schizophrenia inpatients were treated with risperidone for 8 weeks. The positive and negative symptom scale(PANSS) was used for assessment of the efficacy and treatment emergent symptoms scale(TESS) for side effects. The efficacy rate was 75% and 40% marked improvement at the end of study. The onset of action was about one week. The common side effects of risperidone were insomnia and extrapyramidal side effect.All this indicates that risperidone is effective and safe in the treatment of first-episode schizophrenia.