产科母婴同室足月新生儿黄疸的早期干预

Early intervention of jaundice of full-term neonate in the same room with their mother

目的探讨母婴同室足月新生儿黄疸进行早期的动态监测，应用妈咪爱干预以减少其不必要的住院。方法我院980例产科母婴同室足月新生儿为研究对象，每日测经皮胆红素（TSB）筛查黄疸。建议TSB在生后第1天大于85μmol／L，第2天大于137μmol／L，第3-5天大于171μmol／L为黄疸的临界值进行早期干预，予妈咪爱口服。通过每天监测经皮胆红素观察其疗效。结果治疗组新生儿经皮黄疸指数低于对照组（P〈0．05）。结论妈咪爱用于新生儿黄疸早期干预，可迅速降低血清胆红素水平，明显缩短治疗时间，提高治疗有效率，对足月新生儿黄疸干预效果满意。

Objective To investigate the early dynamic monitoring of jaundice of full-term neonates in the same room with their mothers and to reduce unnecessary hospitalization by applying Mamiai intervention. Methods 980 full-term neonates in the same room with their mothers of our hospital were selected as the study subjects and their transcutaneous bilirubin （TSB） was measured daily for the screening of jaundice. It is suggested that TSB higher than 85 μ mol/L on day 1 of birth, higher than 137 μ mol/L on day 2, and higher than 171 μ mol/L on day 3, 4 and 5 be the thresholds of jaundice and necessitate early intervention with Mamiai oral administration. The curative effect was observed through daily monitoring of transcutaneous bilirubin. Results The treatment group had lower transcutaneous bilirubin index than the control group（P 〈 0.05）. Conclusion Application of Mamiai in early intervention of neonatal jaundice can rapidly reduce the serum bilirubin level, obviously shorten treatment time and improve treatment effective rate, showing satisfactory intervention effect on full-term neonatal jaundice.