开胸术后应用舒芬太尼与吗啡的硬膜自控镇痛效果及对肺功能影响的比较

Comparison analgesia effects and effect of sufentanil and morphine on lung function

目的:比较开胸手术后舒芬太尼硬膜自控镇痛和吗啡硬膜自控镇痛的效果及其对患者肺功能的影响。方法:60例开胸手术患者随机分为观察组和对照组,各30例。观察组应用舒芬太尼硬膜自控镇痛,对照组应用吗啡硬膜自控镇痛。观察并比较术后4、8、12、24、48h的视觉模拟镇痛评分(VAS)和用力肺活量(FVC)、第一次用力呼气量(FEV1)。结果:观察组患者术后4、8、12和24h的VAS值明显低于对照组(P<0.05),FVC和FEV1值均显著高于对照组(P<0.05)。结论:在胸科手术患者术后镇痛中,舒芬太尼硬膜外自控镇痛效果优良,且患者肺功能恢复好,值得临床推广应用。

Objective= To compare sufentanil and morphine on lung function. Methods= A total of 60 patients with thoracic surgery were randomly divided into observation group and control group by half. Patients in the observation group had dural analgesia with sufentanil, while patients in the control had morphine dural analgesia. Visual analog pain scale （VAS）, FVC, FEV1 at 4, 8, 12, 24, 48 h were com- pared. Results： VAS at 4, 8, 12 and 24 h of the observation group were significantly lower than the con- trol （P〈0.05）, FVC and FEV1 values of the observation group were significantly higher than the control group （P〈0.05）. Conclusion： For patients with thoracic surgery, sufentanil epidural analgesia not only has excellent analgesic effect, but also is conducive to the recovery of postoperative lung function. It is worth of widely application.