舒血宁注射液治疗短暂性脑缺血发作的疗效分析

Effect of Shuxuening injection on transient ischemic attack

目的：探讨舒血宁注射液治疗短暂性脑缺血发作（TIA）的临床效果。方法：选取2010年10月～2012年12月我院神经内科收治的TIA患者80例，随机分为观察组和对照组，均给予常规抗血小板聚集、抗凝、控制血压、控制血糖等基础治疗，在常规治疗基础上观察组给予舒血宁注射液静滴治疗，对照组加用川芎嗪注射液静滴治疗，疗程7d，比较两组的临床疗效，并检测两组患者出凝血指标改善情况。结果：观察组总有效率显著高于对照组，差异有统计学意义（P〈0．05）；两组患者用药后出凝血指标比较差异均无统计学意义（P〉0．05）。结论：舒血宁注射液对于短暂性脑缺血发作疗效确切，无明显不良反应，值得，临床推广应用。

Objective. To investigate the effect of Shuxuening injection on transient ischemic at- tack. Methods. A total of 80 cases of transient ischemic attack attending Neurology Department, Futian Chinese Medicine Hospital, Shenzhen from October 2010 to December 2010 were selected , randomly di- vided into observation group and control group. Both of patients were given basic treatments, including conventional anti-platelet aggregation, anticoagulation, control of blood pressure and blood glucose, etc. On the basis of the above treatments, patients in the observation group were treated with Shuxuening in- jection, while those in control group with ligustrazine injection. After 7 days, the clinical efficacy in the two groups was compared, and the improvement of bleeding and clotting indexes in both groups were de- tected. Results= The total effective rate in observation group was significantly higher than that of the con- trol group （P〈0.05）. After treated with respective drugs, the bleeding and clotting indexes in the two groups showed no significant difference （P〉0.05）. Conclusions= Shuxuening injection has a good effect on patients with transient ischemic attack and no obvious adverse reaction . It is worth of being promoted clinically. Keywords ：