发热患者血清降钙素原和超敏C反应蛋白意义的临床探讨

Clinical discussion of the significance of serum calcitonin original and hypersensitive c-reactive protein in patients with fever

目的：对发热患者血清降钙素原和超敏C反应蛋白意义进行临床探讨.方法：对300例发热患者及100体温正常者用Sysmex XT-1800I全自动五分类血液分析仪检测血常规,i-CHROMA Read-er免疫荧光分析仪、配套的C反应蛋白检测试剂盒测定hs-CRP,降钙素原测定试剂盒和免疫色谱检测法检测PCT.结果：起病1～6 d,hs-CRP与正常对照组比较差异有统计学意义（P＜0.01）；起病1～2 d和5～6 d PCT和WBC与正常对照组比较差异无统计学意义；起病3～4d PCT、hs-CRP和WBC与正常对照组比较差异有统计学意义（P＜0.01）.结论：发热患者血清如果出现降钙素愿升高情况,可能会导致继发性细菌感染和脓毒血症.

Objective： To discuss the clinical significance of calcitonin original and hypersensitive C-reactive protein in patients with fever. Methods： Blood was performed routine testing by the Sysmex XT-1800I Automated Hematology Analyzer with five classifications; hypersensitive 3C-reactive protein was detected with i-CHROMA Reader Immunofluorescence Analyzer along with the C-reactive protein test kit, test） in 300 cases of From the first to the and procalcitonin was with the procalcitonin test kit （immunochromatographic patients with fever and 100 patients with normal body temperature. Results： 6^h onset day, the hs-CRP was statistically different from that of the normal control group （P〈0.01） ; there were no statistical differences of PCT and WBC between the experimental group and the normal control group at the first to the second day and the fifth to sixth day of onset of the disease; but compared with the normal control group, there were statistical differences of PCT, hs-CRP and WBC between the experimental group and the normal control group at the third to the fourth onset day of the disease （P〈.01）. Conclusion： In patients with fever, if the calcitonin original has been found elevated, it may lead to secondary bacterial infections and sepsis.