摘要
本文报道羧胺醛(7603,甲基亚胺二乙酸香草醛)的毒理学(急性毒性、蓄积毒性和长期慢性毒性)研究和正常人试用情况。结果表明,羧胺醛的毒性是低的;3例志愿健康人试用除注射局部有胀痛感外,未观察到其他毒副作用。
Suo An Quan(7603,5-Methyleneiminodiacetic acid vanillin)is a new chelating agent that showed good effect for decorporation of ^(234)Th and ^(144)Ce in rats.In this paper,the toxicity(LD_(50),accu-mulated toxicity,and chronic toxicity)of Suo An Quan were investigated.It showed that no obvioustoxicity was observed when 7603 was injected intramnscularly at 100 mg/kg·day×30 days in dogs.Suo An Quan had been used in 3 normal human.Except a little sore on the injected region,no evidenttoxic side effects were observed.
出处
《辐射防护》
CAS
CSCD
北大核心
1991年第6期453-456,452,共5页
Radiation Protection
基金
中国科学院(84)科学基金
关键词
羧胺醛
毒理学
络合剂
Chelating Agent
Toxicity
Suo An Quan
Methyleneiminodiacetic Acid Vanillin
