摘要
目的探讨溴隐亭对泌乳素腺瘤术后的治疗效果。方法回顾性分析非侵袭性泌乳素腺瘤15例、侵袭性泌乳素腺瘤6例患者的术后治疗效果。结果术后口服溴隐亭在控制术后高泌乳素血症、随访中控制肿瘤复发方面均与未口服组比较存在显著性差异(P<0.05)。结论肿瘤的生物学性质影响治疗方式的选择和最终预后水平。对于手术切除肿瘤后部分患者仍存在内分泌紊乱的激素异常和临床症状,术后合理地口服溴隐亭能有效恢复垂体正常生理功能,缩小肿瘤和降低肿瘤复发,增强手术效果,提高患者生活质量。
Objective To investigate the effect of bromocriptine in treating postoperative prolactinomas.Methods The postoperative treatment effects in 15 cases of non-invasive prolactinomas and 6 cases of invasive prolactinomas were retrospectively analyzed.Results The postoperative oral bromocriptine had statistical differences in controlling hyperprolactinemia and tumor recurrence during follow up period between the bromocriptine group and the non-bromocriptine group（P ＜ 0.05）.Conclusion The biological properties of the tumor affect the choice of treatment mode and the final prognostic level.The hormone abnormity and clinical symptoms exist in the partial patients after tumor resection.Postoperative rational oral bromocriptine can effectively restore the normal physiological function of pituitary,shrink the tumor,reduce tumor recurrence,increaase the operative effect and improve the quality of life in patients.
出处
《中国药业》
CAS
2013年第21期71-72,共2页
China Pharmaceuticals
基金
重庆市卫生局科研项目
项目编号:2012-2-226
关键词
泌乳素腺瘤
溴隐亭
手术治疗
prolactinomas
bromocriptine
operative treatment
