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血清NT-proBNP水平检测在急诊呼吸困难鉴别诊断中的价值 被引量：7

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摘要 目的探讨血清N端B型钠尿肽前体(NT-proBNP)水平检测在急诊呼吸困难鉴别诊断中的临床价值。方法采用酶联免疫吸附法检测145例急诊呼吸困难患者(75例心源性呼吸困难和70例肺源性呼吸困难)血清NT-proBNP表达水平及LVEF值,比较两组患者血清NT-proBNP表达水平的差异性,以及心源性呼吸困难患者不同心功能分级血清NT-proBNP表达水平与左室射血分数(LVEF)的相关性。结果心源性呼吸困难患者血清NT-proBNP表达水平[(471.40±190.99)pg/ml]明显高于肺源性呼吸困难患者[(84.77±24.17)pg/ml](P<0.05),而LVEF值[(42.04±5.16)%]明显低于肺源性呼吸困难患者[(60.79±7.27)%](P<0.05);心源性呼吸困难患者血清NT-proBNP表达水平随心功能分级加重而逐渐升高,血清NT-proBNP表达水平与LVEF呈负相关(r=-0.79,P<0.05)。结论血浆NT-proBNP表达水平检测对心源性呼吸困难和肺源性呼吸困难的鉴别诊断具有十分重要的临床价值。
作者 邵碧波 冯辉斌
机构地区 黄石市中心医院(湖北理工学院附属医院)重症医学科肾脏疾病发生与干预湖北省重点实验室
出处 《临床肺科杂志》 2013年第12期2286-2287,共2页 Journal of Clinical Pulmonary Medicine
关键词 NT-PROBNP 肺源性呼吸困难 水平检测 鉴别诊断 临床价值 血清 急诊 心源性呼吸困难
分类号 R56 [医药卫生—呼吸系统]
  • 相关文献

参考文献9

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二级参考文献39

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共引文献42

同被引文献59

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引证文献7

二级引证文献19

临床肺科杂志
2013年 第12期

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