摘要
NBS促进的5-溴-1H-吲哚和二(3,4,5-三甲氧基苯基)二硫醚可以在DMF中反应得到标题化合物。该反应在室温下就可以高收率完成,不需要金属催化和其他添加剂。原料易得,后处理操作简单。产物通过1HNMR、MS进行了表征。
5 -Bromo-3-[ （ 3,4,5-trimethoxy-phenyl ） thio ] -1 H- indole was synthesized via NBS-promoted the reaction be-tween 5-bromo-1 H-indole and 1,2-his （ 3,4,5-trimethoxyphe- nyl） disulfide in the solvent DMF. High yield could be ob-tained at room temperature without the use of metal catalyst and other additives. Starting raw could be easily available and post-treatment operation was simple. The structure of the tar-get product was confirmed by NMR and MS.
出处
《化学试剂》
CAS
CSCD
北大核心
2013年第11期1051-1053,共3页
Chemical Reagents
