阻塞性睡眠呼吸暂停低通气综合征患者鼾声间隔期呼吸事件分析

Investigation of respiratory events interval between snores in obstructive sleep apnoea hypopnea syndrome

目的打鼾后无呼吸紊乱事件为单纯鼾声,打鼾后有呼吸紊乱事件的鼾声缺乏明确定义,本研究初步探讨打鼾后有呼吸紊乱事件的特点,为进一步鼾声的分类奠定基础。方法总结在我科因睡眠打鼾就诊152例患者鼾声间隔期呼吸事件发生的特点。结果 24名鼾症和124例阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者整夜睡眠期共记录4 813和41 329次鼾声间隔期。鼾症和OSAHS患者鼾声间隔期存在呼吸事件及比例分别为:①连续打鼾无呼吸紊乱事件(89.15%;53.18%);②仅一次低通气或呼吸暂停事件(2.43%;15.12%);③两次和两次以上紊乱事件(8.42%;31.70%)。鼾症患者睡眠呼吸紊乱指数仅与鼾声间隔期一次紊乱事件相关,OSAHS患者睡眠呼吸紊乱指数与三种现象的发生均相关。结论打鼾后多无睡眠呼吸紊乱事件,OSAHS患者打鼾后二次或二次以上呼吸紊乱事件发生率较高,忽视鼾声后这些现象的存在可能是鼾声分析诊断OSAHS精确度不高的原因。

[ Objective ] To investigate the respiratory events interval between snores. [ Methods ] The respiratory events between snores were obtained from individuals who are suspected of OSAHS pathology and performed full night polysomnography. [Results] 4813 and 41329 intmwal between snores were collected in 14g subjects [24 sim- ple snorers （SS） and 128 OSAHS patients]. The types of respiratory events interval between snores include： no respi- ratory disturbance event （89.15% in SS, 53.18% in OSAHS）; only one respiratory disturbance event （2.43% in SS, 15.12% in OSAHS）; two and more respiratory disturbance event （8.42% in SS, 31.7% in OSAHS）. The RDI was re- lated to all types of respiratory events interval between snores in OSAHS. [ Conclusions ] Nearly half had no respi- ratory disturbance event interval between snores in OSAHS. Our study revealed that it＇s more important to detect two and more respiratory disturbance events interval between snores may be the key to diagnose OSAHS by snore analysis.