同型半胱氨酸与冠状动脉病变的相关性研究

The correlation research between homocysteine and coronary artery lesion degree

目的探讨同型半胱氨酸(Hcy)与冠状动脉病变程度的关系。方法检测108例冠心病(CHD组)患者和84例非冠心病(对照组)患者Hcy水平。结果 CHD组Hcy水平明显高于对照组(P<0.05),AMI组Hcy水平明显高于UAP组和SAP组(P<0.05),UAP组与SAP组的Hcy水平差异无统计学意义(P>0.05)。≥60岁年龄组Hcy水平高于<60岁年龄组,男性Hcy水平高于女性,差异均有统计学意义(P<0.05)。结论 Hcy水平与CHD有密切的关系,Hcy水平越高,CHD越严重。

Objective To investigate the relationship of homocysteine（Hcy） and coronary artery lesion degree. Methods Hey level in 108 cases of coronary heart disease patients （CHD group） and 84 cases of non-coronary heart disease pa- tients （control group） were detected. Results The Hcy level of CHD group was significantly higher than that of control group （P〈0.05）,The Hcy level of AMI group was significantly higher than that of UAP group and SAP group （P〈0.05）, The Hcy level of UAP group and SAP group was not statistically signifieant（P〉0.05）.The Hcy level of patients with the age over 60 was higher than that of patients with age less than 60,the Hcy level of men was higher than that of wom- en, the differences were all statistically significant（P〈0.05）. Conclusion Hey level has close relationship with CHD,and the higher the level of Hey,the more serious CHD is.