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Fas信号转导蛋白及其作用 被引量:3

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摘要 Fas介导的细胞凋亡对细胞的增殖调控起重要作用。Fas受体与其相应配体结合后 ,通过蛋白死亡区的相互作用激活一系列信号蛋白及蛋白酶 ,引起多种底物的降解 ,导致细胞出现凋亡的生化及形态学改变。
出处 《国外医学(生理病理科学与临床分册)》 2000年第6期437-439,共3页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
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  • 1宋勇,毛宝龄,夏锡荣,黎介寿.LPS对大鼠肺泡Ⅱ型细胞Fas抗原表达及细胞凋亡的影响(英文)[J].医学研究生学报,1999,12(4):229-233. 被引量:2
  • 2石运伯,王若翔,时玉舫.细胞凋亡的分子机理[J].生命科学,1996,8(3):8-12. 被引量:15
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  • 7Nagata S,Golstein P. The Fas death factor. Science,1995,267:1449-1456.
  • 8Bennett MW,O'Connel J,O'Sullivan GC,et al.The Fas counterattack in vivo apoptotic depletion of tumor-infiltrating lymphocytes associated with Fas Ligand expression by human esophageal carcinoma.J Immunol,1998,160:5669-5673.
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