影响肝癌自发破裂的危险因素及预后研究

Research on risk factors and prognosis of affecting spontaneous rupture of liver cancer

目的分析影响肝癌自发破裂的危险因素,寻找合适的肝癌自发破裂的治疗方法。方法从本院2008年7月至2012年7月确诊的肝癌患者中,选取145例自发破裂的肝癌患者和145例未破裂的肝癌患者进行相关因素比较,并采用单因素分析和多因素回归分析方法分析引发肝癌自发破裂的危险因素。结果多因素回归分析显示,高血压、突出肝表面、肝硬化、肝外侵犯及肿瘤大于5 cm是肝癌自发破裂的预测因素。结论对于伴有高血压、肝硬化、突出肝表面、肝外侵犯及肿瘤直径大于5 cm的患者,应密切注意肝癌自发破裂的风险,根据患者体征选择合适的治疗方法。

To find the appropriate treatment of spontaneous rupture of liver cancer analyzed by the risk factors of spontaneous rupture of liver cancer. Methods One hundred and forty-five cases of spontaneous rupture of liver cancer patients and 145 cases of patients without rupture were selected from Jul. 2008 to Jul. 2012 in our hospital, and risk factors of spontaneous rupture of liver cancer were analyzed using single factor analysis and multifactor regression analysis methods. Results The predictors of spontaneous rupture of liver cancer were hypertension, the surface of the liver, liver cirrhosis, liver invasion and tumor diameter greater than 5 cm analyzed by multiple factors regression analysis. Conclusion The patients accompanied by hypertension, liver cirrhosis, prominence to the surface of the liver, liver invasion and tumor with larger than 5 cm in diameter, should be paid close attention to the risk of spontaneous rupture of liver cancer, and the appropriate treatment is choose according to the patient signs.