摘要
肝移植术后急性激素拮抗性排斥反应(ASRR)的特点是患者对传统大剂量激素治疗反应差。目前认为抗体介导的排斥反应是发生ASRR的原因之一。报道显示多种抗排斥药物对其治疗有效,但目前尚无规范的治疗方案。本文系统回顾分析了ASRR的高危因素、发生机制、诊断标准和治疗策略。
The main feature of acute steroid-resistant rejection (ASRR) after liver transplantation is a lack of re- sponse to steroids. Although some effective immunosuppres- sants are available, there is no uniform treatment presently available. This paper will focus on exploring the mechanism of ASRR and formulating individually approached strategies.
出处
《中华肝胆外科杂志》
CAS
CSCD
北大核心
2013年第11期877-880,共4页
Chinese Journal of Hepatobiliary Surgery
基金
浙江省科技厅肝脏移植创新团队项目(2009R50038)
关键词
肝移植
急性激素拮抗性排斥反应
诊
断
治疗
Liver transplantation
Acute steroid-re-sistant rejections~ Diagnosis~ Treatment