期刊文献+

出生体重与学龄前儿童血压关系的研究 被引量:3

A study on the relationship between birth weight and preschool children's blood pressure
下载PDF
导出
摘要 目的分析出生体重与学龄前儿童收缩压(SBP)、舒张压(DBP)的关系。方法选择在上海市闵行妇幼保健院产科出生,于2006年3月至2010年11月接受常规健康体检的2—6岁儿童,采用电子血压计测量SBP、DBP和心率,并测量身高和体重。血压评价参照1997年“日本学龄前儿童正常血压和高血压参考值”,以SBP或DBP≥其性别、年龄相对应的%诊断为高血压。采用多元线性回归分析出生体重与血压的关系,多因素Logistic回归模型分析儿童期患高血压风险的危险因素。结果4642名学龄前儿童进入分析,其中男性2458例(53%);低出生体重儿占3.2%(148/4642),巨大儿占5.4%(251/4642)。男童SBP水平和高血压患病率均高于女童(P分别为〈0.001和0.002)。低出生体重儿SBP、DBP与正常出生体重儿童无明显差异(P分别为0.492和0.398);巨大儿DBP低于正常出生体重儿童(P=0.003)。多因素Logistic回归显示低出生体重儿、巨大儿与发生儿童高血压无统计学关联,而心率高于平均水平发生高血压的危险增高,OR=2.55,95%CI=1.96~3.3l。结论在学龄前儿童中,男童SBP高于女童。未发现低出生体重、巨大儿与儿童期患高血压有统计学关联;心率、体重对血压水平的影响较为明显。 Objective In order to find out the relationship between birth weight and systolic and diastolic blood pressure in preschool children. Methods Date for 4 642 healthy preschool children aged 2 to 6 were collected. All these children were born in Shanghai Minhang Maternal and Child Health Hospital. After rest in the sitting position for 5-10 rain, the blood pressure (BP) and heart rate (HR) were measured on the right arm at the level of the heart, using appropriate size of cuff, by automated BP recorder (Model 45NEO-E6, Welch Allyn, USA). Elevated blood pressure was defined as systolic blood pressure (SBP)and/or diastolic blood pressure(DBP) equal or greater than the 95th percentile for gender and age, according to the reference based on Japanese preschool children(1997). Low birth weight was defined as 〈2 500 g and macrosomia as ~〉4 000 g. Multiple regression models were used to analyze the association between birth weight and childhood hypertension. Results In total 4 642 children were analyzed in this study, with 2 458 (52.9%) being boys. The proportions of low birth weight and macrosomia were 3.2% ( 148/ 4 642) and 5.4% (251/4 642) ,respectively. The prevalence rate of hypertension was more common in boys than girls(9.4% vs 6.9% ,P 〈 0.05 ). Trend of negative correlation between birth weight and childhood DBP was observed in children with birth weight over 4 000 g. With gender, age, heart rate, body height and body weight adjusted, the relationship between birth weight and childhood hypertension was not significant in either low birth weight or macrosomia group. Rapid heart rate may increase the risk of hypertension at childhood ( OR = 2.55, 95% CI : 1.96 - 3.33 ). Conclusion Blood pressure levels of preschool children were not significantly associated with birth weight. Rapid heart rate may increase the risk of hypertension.
出处 《中国循证儿科杂志》 CSCD 2013年第5期379-382,共4页 Chinese Journal of Evidence Based Pediatrics
关键词 出生体重 学龄前儿童 高血压 Birth weight Preschool children Hypertension
  • 相关文献

参考文献24

  • 1Andersson SW, Lapidus L, Niklasson A, et al. Blood pressure and hypertension in middle-aged women in relation to weight and length at birth: a follow-up study. Journal of Hypertension, 2000, 18(12) : 1753-1761.
  • 2Campbell Dm Fau Hall MH, Hall Mh Fau Barker DJ, Barker Dj Fau Cross J, et al. Diet in pregnancy and the offspring~ blood pressure 40 years later. Br J Obstet Gynaecol, 1996, 103 (3) : 273-280.
  • 3Hales C, Barker D, Clark P, et al. Fetal and infant growth and impaired glucose tolerance at age 64. BMJ, 1991,303 (6809) : 1019-1022.
  • 4Barker D, Gluckman PD, Godfrey KM, et al. Fetal nutrition and cardiovascular-disease in adult life. Lancet, 1993, 341 (8850) : 938-941.
  • 5Barker DJ, Osmond C, Law CM. The intrauterine and early postnatal origins of cardiovascular disease and chronic bronchitis. J Epidemiol Comnmnity Health, 1989, 43 (3) : 237- 240.
  • 6Horta BL, Barros FC, Vietora CG, et al. Early and late growth and blood pressure in adoleseenee. J Epidemiol Community Health, 2003, 57(3) : 226-230.
  • 7Uiterwaal CS, Anthony S, Launer L, et al. Birth weight, growth, and blood pressure: an annual follow-up study of children aged 5 through 21 years. Hypertension, 1997,30(2 Pt 1) :267-271.
  • 8Huxley R, Neil A, Collins R. Unravelling the fetal origins hypothesis: is there really an inverse association between birthweight and subsequent blood pressure? Lancet, 2002, 360 (9334) : 659-665.
  • 9Laor A, Stevenson DK, Shemer J, et al. Size at birth, maternal nutritional status in pregnancy, and blood pressure at age 17: population based analysis. BMJ, 1997,315(7106): 449-453.
  • 10Matthes JW, Lewis PA, Davies DP, et al. Relation between birth weight at tern1 and systolic blood pressure in adolescence BNJ, 1994, 308(6936) : 1074-1077.

二级参考文献24

  • 1林良明,刘玉琳,张新利,曹兰华,米杰.1998年中国育龄妇女贫血情况调查[J].中国生育健康杂志,2002,13(3):102-107. 被引量:42
  • 2廖文科.1995年全国学生体质健康调查[J].中华预防医学杂志,1997,31(1):42-43. 被引量:84
  • 3卫生部妇幼卫生司 九市儿童体格发育调查协作组.1995年中国九市7岁以下儿童体格发育调查研究[R].北京:北京医科大学、中国协和医科大学联合出版社,1998.1-10.
  • 4Mi J, Law C, Zhang KL, et al, Effects of infant birthweight and maternal body mass index in pregnancy on components of the insulin resistance syndrome in China[J]. Ann Intern Med,2000,132(4):253-260.
  • 5Miller HC, Hassanein K. Diagnosis of impaired fetal, growth in newborn infants [J]. Pediatrics, 1971,48 (4):511-522.
  • 6Xu B, Rantakallio P. Mortality and hospitalizations of 24-year-old members of the low birth weight cohort in northern. Finland[J].Epidemiology, 1998,9(6):662-665.
  • 7Silverman M, Lung function and low birth weight [J], Arch Dis Child ,2003,88 (8):743.
  • 8Guerra A, Rego C, Vasconcelos C, et al. Low birth weight and cardiovascular risk factors at school age [J]. Rev Port Cardiol,2004,23(3):325-339.
  • 9Breslau N, Paneth N, Lucia V, Tile lingering academic deficits of low birth weight children [J]. Pediatrics, 2004.114(4): 1035-1340.
  • 10Forsdahl A, Are poor living conditions in childhood and adolescence an important risk factor for arteriosclerotic heart disease?[J]. Br J Prey Soc Med,1977,31 (2):91-95.

共引文献5205

同被引文献23

引证文献3

二级引证文献23

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部