自拟滋肾调更汤治疗围绝经期综合征36例

Clinical Observation of Modified Zishen Tiaogeng Decoction on Treating 36 Cases with Perimenopausal Syndrome

目的:观察自拟滋肾调更汤治疗围绝经期综合征的疗效。方法:将72例患者随机分为自拟滋肾调更汤组(治疗组)36例和替勃龙片组(对照组)36例。两组临床观察均以2个月为1个疗程,共观察1个疗程,以临床疗效及治疗前后Kupperam Index症状评分(下称KI评分)改善作为观察指标。结果:治疗前后两组KI评分自身比较,均见P<0.01,差异有统计学意义,治疗后组间比较P>0.05,无显著性差异;治疗后两组围绝经期症状均有不同程度改善,但治疗组对很多症状及症状改善程度明显(P<0.05,P<0.01),治疗后两组组间比较,差异无显著性(P>0.05)。结论:自拟滋肾调更汤治疗围绝经期综合征疗效显著。

Objective：To observe the eurative effect of modified Zishen Tiaogeng Decoction on treating perimenopausal syndrome. Methods ：72 eases were randomly divided into two groups, and treated with modified Zishen Tiaogeng Decoetion （ treatment group） or Tibolone （control group） for two months as a course. Then, before and after treatment, menopausal syndrome was observed using the clinical effects and Kupperman Index（KI） as the indexes. Results：Before and after treatment, KI had statistical difference （P 〈0. 01 ） in two groups. And there was no significant difference between them after the treating （P 〉 0. 05 ）. The symptoms of perimenopausal syndrome were both improved in two groups. But the treatment group had more changes than the con- trol group. Conclusion：Modified Zishen Tiaogeng Decoction was effective on treating perimenopausal syndrome.