稳心颗粒治疗糖尿病引起的心律失常临床观察

Clinical Observation on Effect of Wenxin Granules in Treatment of Diabetes-Induced Arrhythmia

目的:探讨稳心颗粒治疗糖尿病引起的心律失常的临床疗效。方法:回顾性分析2010年4月—2012年2月收治的100例老年糖尿病合并心律失常患者,随机分为试验组与对照组,每天3次给予对照组患者150 mg的心律平片,每天3次给予试验组患者步长稳心颗粒1袋(为9 g),连续用药4周为1个疗程,密切观察两组老年糖尿病合并心律失常患者的临床治疗效果。结果:(1)两组老年糖尿病合并心律失常患者经过1个疗程的治疗后,试验组显效为16例,有效为27例,对照组显效为13例,有效为18例。试验组的总有效率(86.0%)明显高于对照组的总有效率(62.0%)(t=2.526,P=0.025<0.05);(2)试验组动态心电图改善:显效为21例,有效为20例,对照组动态心电图改善:显效为17例,有效为19例。试验组的总有效率(82.0%)明显高于对照组的总有效率(72.0%)(t=3.115,P=0.018<0.05)。结论:稳心颗粒对于治疗老年糖尿病患者合并心律失常具有较好的疗效,明显改善了患者的临床症状,值得在临床上推广使用。

Objective ： To study the effect of Wenxin Granules in the treatment of diabetes - induced arrhythmia. Methods ： Retrospective analysis was used for patients during the period fi＇om April 2010 to February 2012 in our hospital. 100 cases of elderly diabetic patients with arrhythmia were randomly divided into experimental and control groups. Propafenone tablets of 150 mg was given to the control group patients three times a day, and three times a day administration of the test patients Buchang Wenxin a bag of particles （9 g） was for patients in experimental group. The clinical outcomes of the two groups were observed. Results： （ 1 ） After a course of treatment, the experimental group was markedly effective in 16 cases, effective 27 cases, and in the control group that were 13 cases, efiective in 18 cases. Experimental group＇s total effective （86.0%） was significantly higher than the total efficiency （62.0%） of the control group（ t = 2. 526 ,P = 0. 025 〈 0.05 ）. （2） The experimental group dynamic ECG improvement： 21 cases markedly effective and 20 cases effective;in the control group 17 cases markedly effective and 19 cases effective. The total effective of experiment group （82.0%） was significantly higher than the total efficiency （72.0%） of the control group（ t = 3. 115, P = 0. 018 〈 0.05 ）. Conclusion ： Wenxin Granules has good effect for the treatment of elderly patients with diabetes arrhythmia,and it can significantly improve the clinical symptoms and worthy of appliation in clinical practice.