自制中药联合心理干预对重症急性胰腺炎的治疗及生活质量的评价

Evaluation of Quality of Life and Curative Effect of Self-Made Traditional Chinese Medicine Combined with Mental Intervention Treating Severe Acute Pancreatitis

目的:探讨自制中药联合心理干预对重症急性胰腺炎(SAP)的治疗及生活质量的影响。方法:70例SAP患者被随机分为干预组和常规组。常规组:34例患者,接受常规治疗;干预组:36例患者,在常规治疗的基础上采取中药联合心理干预治疗。结果:干预组SAP患者治疗后腹压痛、腹胀、腹痛消失时间及恢复排气时间分别是(1.675±4.014)天、(2.171±4.482)天、(3.121±4.141)天、(3.476±3.922)天,常规组分别是(3.892±4.071)天、(4.242±3.231)天、(4.941±3.211)天、(5.321±3.301)天(皆P<0.05);干预组SAP患者住院时间和住院总费用分别为(15.501±1.751)天、(1.112±0.424)万元,少于常规组的(19.352±1.692)天和(2.292±1.081)万元(皆P<0.01);干预组假性囊肿、胰周感染及MOF发生率分别是33.3%、13.9%、22.2%,显著低于常规组(58.8%、41.2%、47.1%,皆P<0.05);干预组干预前SAS、SDS评分分别为(56.521±4.362)分和(55.712±5.361)分,常规组治疗前SAS、SDS评分分别为(56.622±4.341)分、(55.811±5.442)分;干预组干预后SAS、SDS评分分别为(49.311±3.342)分和(48.412±3.361)分,常规组治疗后SAS、SDS评分分别为(52.312±3.361)分、(51.971±3.262)分;干预组SAP患者干预后SAS及SDS评分也明显低于常规组,且患者及家属满意程度也显著高于常规组(91.7%vs70.6%,P<0.01)。结论:使用中药治疗SAP的同时对患者联合采取心理干预措施,可以增强SAP的治疗效果,减少SAP患者住院时间和医疗总费用,并减少并发症,同时降低SAP患者抑郁和焦虑情绪,提高患者及其家属的满意程度。

Objective ：To research the quality of life and curative effect of self- made traditional Chinese medicine combined with mental intervention treating severe acute pancreatitis. Methods ：70 patients with severe acute pancreatitis were divided into intervention group and routine group. Routine group：34 patients all received routine treatment. Intervention group：all 36 patients received traditional Chinese medicine combined with mental intervention on the basis of routine treatment. Results ：The recovey time of abdominal tenderness,abdominal distention,abdominal pain, and restoring fart in intervention group were （1. 675 ± 4. 014） days, （ 2. 171 ± 4. 482 ） days, （ 3. 121 ± 4. 141 ） days, （ 3. 476 ± 3. 922 ） days, respectively, less than those of routine grnup [ （ 3. 892 ± 4. 071 ） days, （4. 242 ± 3.231 ） days, （4. 941 ± 3.211 ） days, （ 5.321 ± 3.301 ） days, all P 〈 0. 05 ]. The hospitalization cost and time of intervention group were （ 15. 501 ± 1.751 ） days, （ 1. 112 ± 0. 424） million respectively, less than that of routine group [ （ 19. 352 ± 1. 692 ） days and （2. 292 ± 1.081 ）million, all P 〈 0. 01 ]. The incidences of panereatic pseudoeyst, peripancreatic infection and MOF in intervention group were 33.3%, 13.9% ,22.2%, respectively, less than those in routine group （58. 8% ,41.2% ,47. 1% ,all P 〈0.05）. The SAS and SDS scores before intervention in intervention group were （56. 521 ± 4. 362） points and （55. 712± 5. 361 ） points respectively. The SAS and SDS scores in routine group before treatment were （56. 622 ± 4. 341 ） points and （55.811 ± 5. 442） points, respectively. The SAS and SDS scores after intervention in intervention group were （49.311 ± 3. 342） points and （48. 412 ± 3. 361 ） points respectively. The SAS and SDS scores in routine group after treatment were （52. 312±3. 361 ） points and （51. 971 ±3. 262） points respectively. The SAS and SDS scores in intervention group were lower. The satisfaction rate was higher in intervention group （91.7% VS 70.6% , P 〈 0. 01 ）. Conclusion：The use of traditional Chinese medicine combined with psychological intervention measures treating patients with severe acute pancreatitis can enhance the curative effect of severe acute pancreatitis,and reduce the hospitalization time and the total cost of patients,and reduce complications rates,and reduce depression and anxiety in severe acute pancreatitis patients,and also can improve the satisfaction degree of the patients and their families.