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TSHR蛋白在恶性肿瘤组织表达及其生物学意义 被引量:2

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摘要 促甲状腺激素受体(thyroid stimulating hor-mone receptor, TSHR)是调控甲状腺细胞生长、分化的主要受体,其异常表达是获得性、遗传性或先天性甲状腺疾病的重要原因之一。近几年有研究发现甲状腺癌常有TSHR表达增加。国外有学者研究发现TSHR—mRNA在肺癌、前列腺癌和结肠癌等呈现过度表达。TSHR蛋白与恶性肿瘤之间的关系至今国内罕见报道。本研究通过检测多种恶性肿瘤组织TSHR蛋白表达,旨在了解TSHR与恶性肿瘤发生发展之间的关系。
出处 《中国实验诊断学》 2013年第11期2076-2078,共3页 Chinese Journal of Laboratory Diagnosis
基金 辽宁省大连市科技计划发展基金(2011E15SF107)
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参考文献15

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