(S)-4-(2-甲基丁基)-4'-(4-丙基环己基)-2-氟联苯的合成及性能研究

Synthesis and properties of( S)-4-( 2-methylbutyl)-4'-( 4-propylcyclohexyl)-2-fluoro-biphenyl

以(S)-(2-甲基丁基)苯为原料,经碘代和Suzuki偶联四步反应,合成了手性液晶(S)-4-(2-甲基丁基)-4'-(4-丙基环己基)-2-氟联苯,总收率11.4%,纯度99.2%,并采用IR、MS、1H NMR及元素分析对其结构进行了表征。结合差示扫描量热仪(DSC)和偏光显微镜(POM)研究了目标化合物的介晶性,并采用Cano’s wedge法测定了目标化合物的扭曲力。

The target compound （ S ） - 4- （ 2-methylbutyl ） - 4＇ - （ 4 -propylcyclohexyl ） -2-fluoro-biphenyl was synthesized via a four step reactions in a yield of 11.4%, the purity of 99.2%. The structure identifica- tion was performed by IR, MS, 1H NMR. The mesomorphic property of objective compounds was investiga- ted by differential scanning calorimetry （DSC） and polarizing optical microscopy （POM）, and the helix twisting power（HTP） was researched by Cano＇ s wedge method.