食源性和病原性金黄色葡萄球菌分离鉴定和耐药性研究

Isolation, Identification and Drug Resistance of Foodborne and Pathogenic Staphylococcus aureus

目的了解食源性与病原性金黄色葡萄球菌分布及耐药情况,为由该菌引起的食物中毒和临床用药提供依据。方法采集食品和医院感染病人标本进行金黄色葡萄球菌分离鉴定及药敏试验。结果食品中沙拉金黄色葡萄球菌污染率最高为15.14%,56.84%的医院分离株来自呼吸道标本痰液,耐甲氧西林金黄色葡萄球菌(MRSA)整体耐药率明显高于甲氧西林敏感金黄色葡萄球菌(MSSA),病原性金黄色葡萄球菌耐药性高于食源性金黄色葡萄球菌。结论加强食源性金黄色葡萄球菌的监测,对于金黄色葡萄球菌的感染治疗应根据药敏结果选择合理的抗生素。

Objective To investigate the distribution and drug resistance of foodborne and pathogenic Staphylococcus aureus,and provide a scientific basis for clinical treatment of food poisoning.Methods The food samples and the specimens of infection patients were collected randomly.Staphyphoccocus aureus was isolated and identified.And drug susceptibility test was performed using minimal inhibitory concentration （MIC）.Results Among the food samples,15.14 ％ of salad were Staphyphoccocus aureus positive.56.84 ％ isolates of pathogenic Staphyphoccocus aureus were separated from patients with respiratory infection.The drug resistance rate of MRSA was significantly higher than that of MSSA.And the drug resistance rate of pathogenie Staphyphoccocus aureus was also higher than that of foodbrone Staphyphoccocus aureus.Conclusions Monitoring foodborne Staphylococcus aureus should be strengthened,and using antibiotics to treat Staphylococcus aureus infection should be based on the results of susceptibility test.