期刊文献+

γ相机点源扩展函数的研究 被引量:1

Research on a High-sensitivity Small Animal SPECT System
下载PDF
导出
摘要 采用探测器几何效率推导了高灵敏度SPECT系统的点源扩展函数,指出了考虑探测器晶体厚度修正的必要性,在小型γ相机上用99mTc的实验结果证明了这一过程,并指出取消准直器在大幅提高灵敏度的同时能够成像的基本根据。在此基础上,讨论了高灵敏度SPECT的灵敏度和空间分辨率,指出了进行小动物成像的可行性;Rose标准的讨论指出灵敏度的大幅提高,明显削弱了背景噪音带来的图像分辨影响,使得动态过程的成像能拥有很好的时间分辨率。 Geometric efficiency was used to derive the point spread function ( PSF) of a SPECT system which u-ses no collimator .The thickness of the NaI crystal was also considered and a modification of the PSF was made . An experiment with the γcamera was used to support the derivation .It showed that the system had a high sensi-tivity and provided an acceptable image at the same time .Based on above results , the sensitivity and resolution of the no-collimator system was discussed to show the potential of the system in small animal imaging .Then Rose criterion was introduced to show that with a high sensitivity the influence of the noise was weakened and a better time resolution in dynamic imaging was provided .
出处 《核电子学与探测技术》 CAS CSCD 北大核心 2013年第9期1134-1138,共5页 Nuclear Electronics & Detection Technology
关键词 高灵敏度 点源扩展函数 厚度修正 Rose标准 high sensitivity point spread function thickness modification Rose criterion
  • 相关文献

参考文献9

  • 1Franc B L, Acton P D, Marl C, et al. Small - animal SPECT and SPECT/CT: important tools for preclinical investigation [ J ]. J. Nut1. Med. , 2008, 49 (10) : 1651 - 63.
  • 2Hagooly A, Rossin R, Welch MJ. Small molecule re- ceptors as imaging targets [ J . Handb Exp Pharma- col, 2008, 185(2) : 93 - 129.
  • 3Jaszczak R J, Li J, Wang H, et al. Pinhole collima- tion for ultra - high - resolution, small - field - of - view SPECT[J]. Phys. Med. Biol., 1994, 39(3): 425 - 437.
  • 4Kastis G A, Furenlid L R, Wilson D W,et al. Com- pact CT/SPECT small - animal imaging system [ J ]. IEEE Trans. Nuel. Sei. ,2004, 51 ( 1 ) : 63 - 67.
  • 5Mitchell G S, Cherry S R. A high- sensitivity small animal SPECT system [J. Phys. Ned. Biol. ,2009, 54(5) :1291 - 1305.
  • 6赵经武,苏为宁.断层屏蔽SPECT成像法探讨[J].核技术,2006,29(8):638-640. 被引量:4
  • 7Webb S, Flower M A, Ott R J. Geometric efficiency of rotating slit - collimator for improved planar gamma -camera imaging [J]. Phys. Med. Biol. ,1993, 38 (5) : 627 -638.
  • 8Lodge M A, Webb S, Flower M A,et al. A Prototype Rotating Slat Collimator for Single Photon Emission Computed Tomography[ J. IEEE Trans. Med. Ima- ging. ,1996, 15(4): 500-511.
  • 9Webb S, Johnson C V. The perception of detail in ra- dioisotope images with Gaussian noise [ J ]. Phys. Med. Biol. ,1990, 35(8): 1145-151.

二级参考文献13

  • 1Jaszczak R J, Chang L T, Murphy Ph. IEEE Trans Nucl Sci, 1979, 26:610-613
  • 2Guerra A D, Damiani C, Domenico G D, et al. IEEE Trans Nucl Sci, 2000, 47(6): 1537-1540
  • 3Habte F, Stenstrom P, Rillbert A, et al. Nucl Instr Meth Phys Res, 2001, A 471:80-84
  • 4Green M V, Seidel J, Vaquero J J, et al. Computerized Medical Imaging and Graphics, 2001, 25:79-86
  • 5Jan B A Hanraken, Kora de Bruin, Morgan Shehata, et al.Journal of Nuclear Medicine, 2001,42(12): 1863-1869
  • 6Bouwens L, Van de Walle R, Nuyts J, et al. Computerized Medical Imaging and Graphics, 2001, 25:117-126
  • 7Webb S, Binnie D M, Flower M A, et al. Phys Med Biol,1992, 37:1095-1108
  • 8Webb S, Flower M A, Ott R J. Phys Med Biol, 1993, 38:627-638
  • 9Lodge M A, Bennie D M, Flower M A, et al. Phys Med Biol, 1995, 40: 427-448
  • 10Lodge M A, Webb S, Flower M A. IEEE Trans Med Imag,1996, 15(4): 500-511

共引文献3

同被引文献7

引证文献1

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部