清热利湿通络方治疗急性痛风性关节炎32例临床观察

Clinical Observation of Qingre Lishi Tongluo Recipe for Acute Gouty Arthritis:A Report of 32 Cases

目的:观察清热利湿通络方治疗急性痛风性关节炎的临床疗效。方法:将62例患者随机分为2组。治疗组32例采用清热利湿通络方加减口服,每天2次,连续服用10天;对照组30例,予口服尼美舒利分散片,每次0.1g,每天1次,连续服用10天。结果:2组疗效经Ridit分析,差异无显著性意义(P>0.05);治疗后治疗组血尿酸(BUA)、谷丙转氨酶(ALT)均低于对照组(P<0.05)。结论:清热利湿通络方治疗急性痛风性关节炎疗效确切,且有一定降低血尿酸作用,无明显短期毒副反应。

Objective： To evaluate the effect of Qingre Lishi Tongluo Recipe, a Chinese herbal formula with the actions of clearing heat, removing dampness and dredging collaterals, for treatment of acute gouty arthritis. Methods： Sixty-two cases of acute gouty arthritis were randomly allocated to the treat- ment group（n=32） and the control group（n=30）. The treatment group was given oral use of Qingre Lishi Tongluo Recipe twice per day for 10 continuous days, and the control group was given oral use of Nime- sulide dispersible tablets 0.1g per time, once per day, lasting 10 continuous days. The clinical symptoms of joints and related hematological indexes were observed. Results： The effect of the two groups had no statistical significance（P〉0.05）. The blood uric acid （BUA） and alanine aminotransferase（ALT） levels of the