脐血有核红细胞与胎儿宫内窘迫的关系

The Relationship Between Nucleated Red Blood Cells in Umbilical Vein and Fetal Distress

为探讨脐血有核红细胞 (NRBC)与胎儿宫内窘迫的关系 ,作者采用细胞记数法对 12 4例正常胎儿脐血及 2 5例胎儿宫内窘迫脐血进行了比较研究 ,根据脐动脉血象再将胎儿分为 p H值正常组、轻度酸中毒组和酸中毒组。结果 :胎儿宫内窘迫组脐血 NRBC计数 (8.6 8± 7.6 2个 / 10 0 WBC)明显高于正常胎儿组脐血 NRBC计数(3.2 5± 3.0 7个 / 10 0 WBC)。酸中毒组 NRBC计数亦明显高于 p H正常组及轻度酸中毒组 (P <0 .0 5 ) ,分别为15 .0 8± 6 .0 6个 / 10 0 WBC,3.19± 2 .90个 / 10 0 WBC和 2 .5 0± 1.6 4个 / 10 0 WBC。由此提示 。

This study was aimed to explore the relationship between nucleated red blood cells(NRBC) in umbilical vein and fetal distress. NRBC in umbilical vein was counted in 24 normal fetuses and 25 distressed fetuses, and based on the blood gas analysis of umbilical artery blood, the fetuses were divided into the pH normal group, mild acidosis group and acidosis group. The results showed that NRBC count was significantly higher in distressed fetuses(8.68±7.62/100 WBC) than in normal fetuses (3.25±3.07/100 WBC)( P <0.05). NRBC count was significantly higher in acidosis group (15.08±6.06/100 WBC) than in mild acidosis group (2.50±1 64/100WBC) and normal pH group (3.19±2.90/100 WBC) ( P <0.05). No difference in NRBC count was found between the normal pH group and mild acidosis group ( P >0.05). These data suggested that NRBC could be used as a diagnostic marker for chronic fetal distress.