腹腔镜子宫肌瘤剔除术和腹腔镜子宫切除术治疗子宫肌瘤短期临床疗效比较

COMPARISON OF THE SHORT-TERM CLINICAL THERAPEUTIC EFFECTS OF LAPAROSCOPIC MYOMECTOMY WITH LAPAROSCOPIC HYSTERECTOMY ON UTERINE FIBROIDS

目的比较腹腔镜子宫肌瘤剔除术(LM)和腹腔镜子宫切除术(LH)用于治疗症状性子宫肌瘤的短期并发症发病率和生活质量。方法通过前瞻性,观察性研究明确手术对象。参加研究的病例完全知情同意,每个参与者都被要求完成SF-12健康的调查在手术前、术后7d和手术后28d。详细记录术后4周内并发症的发病率、手术时间、出血量、住院天数等相关数据。进行统计分析。结果共有70例患者参与本次研究,其中包括40例接受LM和30例LH。LH组手术时间为(209.93±14.56)min比LM组(161.90±12.20)min稍长,差异有统计学意义(P<0.05)。然而,没有发现二者之间SF-12评分、住院时间及短期并发症等差异有统计学意义(P>0.05)。结论子宫肌瘤患者想要保守性手术治疗,LM是可行的选择。二种手术的短期并发症发病率和对生活质量的影响没有明显差别。

Objective To compare the short- term conplication incidence and life quality after laparoscopic hysterectomy （LH） and laparoscopic myomectomy （LM） in treatment of symptomatic uterine fibroids. Methods The operative subjects were chosen based on a prospective and observational study. All the patients who participated in the study gave their complete informed consents, and each patient was required to complete SF- 12 health investigation before the operations, in 7 days after the operations and in 28 days after the operations. Data on the complication incidence, operative time, blood loss and length of stay and so on in 4 weeks after the operations were recorded in detail. And then the data were statistically analyzed. Resuits Totally 70 patients participated in the study （recruitment time： from January 1 of 2012 to December 31 of 2012）, including 40 patients who underwent LM and 30 patients who underwent complete LH. The average operative time of the complete LH group was （209.93 ± 14.56）rain, while that of the LM group was （161.90 ± 12.20）min, and the former was a little longer （P = 0.02）. But no difference in SF-12 score, blood loss, length of stay or shortterm complication were observed. Conclusion LM is a feasible choice for patients with uterine fibroids who want conservative operative therapy, There is no significant difference in shortterm complication incidence or effects on the life quality between the two operations.