中西医结合治疗恶性肺癌胸腔积液80例临床疗效研究

Study of the clinical effect of integrated chinese and western medicine on 80 cases of malignant lung cancer with pleural effusion

目的本研究旨在分析中西医结合对治疗恶性肺癌胸腔积液的临床疗效,为临床中提高肺癌患者生存质量及减轻药物毒副作用提供一定指导。方法将在该院接受治疗的80例恶性肺癌胸腔积液患者按就诊时间及治疗方法的不同分为对照组及结合组各40例。对照组采用引流管引流胸腔积液后注入顺铂和乌体林斯注射液进行治疗。结合组则在对照组的治疗基础上,配合中药泻肺汤合苓桂术甘汤进行口服治疗(中西医结合)。治疗结束后对两组进行临床疗效及不良反应反应评价。结果中西医结合治疗组KPS分数升高率为75%,与对照组55%比较,差异有统计学意义(P<0.05);结合组不良反应阳性率为7.5%,与对照组相比较,差异有统计学意义(P<0.05);临床病症缓解率结合组为70%,与对照组52.5%相比,差异有统计学意义(P<0.05)。结论中西医结合对恶性肺癌胸腔积液具有优异疗效,此法应该在临床进行推广,并值得进行下一步研究。

Objective This study aims to analyze the clinical effect of integrated Chinese and western medicine （ICWM） on malignant lung cancer with pleural effusion（MLCPE）, and to provide direction for improving the life quality of lung cancer patients and alleviating adverse reaction. Methods 80 cases of MLCPE patients who were ad- mitted into our hospital were divided into control group and integrated group （each group 40 cases） according to their clinic time and treatment methods. The control group was treated with cis--platinum and utilins after using drainage tube removing the pleural effusion. The integrated group was treated with Chinese medicine Xiefei decoction with Lingguizhugan decoction orally in addition to the treating basis of control group. The clinical effect and adverse reac- tion of two group were evaluated after treatment. Results Compared with control group 55 % ,the KPS score increas- ing rate of integrated group was 75% （P〈0.05）;The positive rate of adverse reaction of integrated group was 7.5%,and the remission rate of integrated group was 70%, compared with control group, there was a significant difference （P〈0.05）. Conclusion ICWM has an outstanding effect on MLCPE,this method should be promoted in clinical therapy and be studied further.