不同方法治疗肛周巨大尖锐湿疣的疗效分析

Analysis of therapeutic effect of different methods in the treatment of perianal giant condyloma acuminata

目的通过对3种不同方法治疗肛周巨大尖锐湿疣的疗效对比分析,寻找更为有效的治疗手段。方法将64例肛周巨大尖锐湿疣随机分为A、B、C组。A组22例采用疣体基底部缝扎手术切除,局部干扰素注入;B组21例采用微波去除疣体后,局部干扰素注入;C组21例仅做疣体基底部缝扎手术切除,局部不作处理。详细记录各组治疗过程、痊愈时间、复发情况、治疗过程中出现的问题等,最终进行比较分析。结果治疗过程中,B组出血量明显小于A组及C组;3组间创面愈合时间差异无统计学意义(P>0.05);治疗结束时B组有效率(95.24%)明显优于A组(72.73%)及C组(42.86%),差异有统计学意义(P<0.05)。结论微波联合干扰素治疗肛周巨大尖锐湿疣,治疗过程出血较少、复发率低、治疗成本低,值得临床借鉴。

Objective To find out a more effective method by clinical comparative study of several different methods in treating perianal giant condyloma acuminata. Methods 64 patients with perianal giant condyloma acumi- nata were randomly divided into 3 groups,A group （n=22） ,B group （n=21） and C group （n=21）. The patients of A group were injected interferon at bases after pointed condyloma has been resected. The patients of B group were treated with interferon on the basis of microwave operation. The patients of C group were treated with wart body re- section. During therapy, a detailed record was made of in treatment process, cure time, recurrence and appearing prob- lems. Finally,a comparative analysis was made of on the above results. Results The blood loss of B group was much less than that in A and C group. And there was no significant difference（P〉0.05） in the wound healing time in the three groups. The effective rate of B group （95. 24%） was higher than that of A group （72. 73%） and C group （42.86%） at the end of treatment,with significant difference （P〈0.05）. Conclusion The treatment of microwave curing united interferon is effective, less bleeding, low recurrence rate and decreases the cost of medical treatment. It deserves the clinical reference in perianal giant condyloma acuminata.