男性肝移植受者性生活状态的调查

Investigation of sexual function of male liver transplant recipients

目的探讨肝移植手术对男性受者性生活状态的影响。方法研究对象为2007年7月至2012年12月在中山大学附属第三医院肝移植中心行肝移植且术后存活半年以上的男性肝移植受者,共69例。采用自制问卷调查与直接询问相结合的方法了解受者发病前、发病后及手术后的性生活状态。调查内容包括性欲状况、阴茎勃起情况(夜间及清晨)、勃起强度、性生活频度、性高潮情况、性生活满意度以及性生活认知情况(性生活对肝功能是否有影响)。结果受者发病后的性欲状况、阴茎勃起强度异常的发生率高于发病前和手术后,两者比较差异均有统计学意义(均为P<0.01)。与发病前比较,受者发病后和手术后性生活频度、性高潮情况、性生活满意度异常的发生率均较高,两者比较差异均有统计学意义(P<0.01或P<0.05);与发病后比较,受者手术后性生活频度、性高潮情况、性生活满意度异常的发生率较低,两者比较差异有统计学意义(均为P<0.01)。夜间及清晨阴茎勃起异常的发生率和性生活认知(认为性生活对肝功能有影响)的几率,发病前、发病后、手术后,两两比较差异均无统计学意义(均为P>0.05)。结论肝移植可改善终末期肝病男性患者的性生活状态。

Objective To observe the influence of liver transplantation on sexual function of male recipients. Methods Sixty-nine male recipients who underwent liver transplantation in Liver Transplantation Center of the Third Affiliated Hospital of Sun Yat-sen University and had post-operative survival for over six months from July 2007 to December 2012, were selected as study objects. Sexual life state before, after onset of disease and after transplantation was investigated by self-made questionnaire and direct inquiry. Investigation contents included sexual status, penile erectile condition （ night time and early in the morning）, erectile strength, sexual frequency, orgasm condition, sexual satisfaction and sexual cognition （whether sexual life could affect liver function）. Results The incidence rates of abnormal sexual status and penile erectile condition of recipients after onset were significantly higher than those before onset and after transplantation （ all in P 〈 0. 01 ）. Compared with those before onset, incidence rates of abnormal sexual frequency, orgasm condition and sexual satisfaction after onset and after transplantation were significantly higher （P 〈 0.01 or P 〈 0. 05 ）. Compared with those after onset, incidence rates of abnormal sexual frequency, orgasm condition and sexual satisfaction after transplantation were significantly lower （ all in P 〈 0. 01 ）. There was no significant difference in the incidence of abnormal penile erectile condition （ night time and early in the morning） and sexual cognition （considered sexual life could affect liver function） in pairwise comparison among those before, after onset and after transplantation （ all in P 〉 0. 05 ）. Conclusions Liver transplantation can improve the sexual function of male patients with end-stage liver disease.