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儿童及青少年2型糖尿病的诊断和治疗 被引量:4

Diagnosis and treatment of type 2 diabetes in children and adolescents
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摘要 儿童及青少年糖尿病一直是威胁儿童及青少年健康成长的重要危险因素,目前儿童及青少年糖尿病中2型糖尿病占很大一部分.对儿童及青少年2型糖尿病的诊断主要是与1型糖尿病的鉴别.儿童及青少年2型糖尿病多伴有肥胖、多囊卵巢综合征(PCOS)、黑棘皮病等,可以通过临床症状、空腹血糖、口服葡萄糖耐量试验(OGTT)、胰岛素自身抗体和C肽水平来诊断儿童及青少年2型糖尿病.儿童及青少年2型糖尿病与1型糖尿病相比,更早、更易出现糖尿病微血管并发症.目前的治疗方案主要有糖尿病健康教育、饮食控制、运动疗法、口服药物和胰岛素治疗. Diabetes has been an important risk factor which threats the health of children and adolescents.Type 2 diabetes accounted for a large part in the amount of children and adolescents with diabetes.Diag-nosis of type 2 diabetes in children and adolescents is mainly to identify from type 1 diabetes mellitus.Many children and adolescents with type 2 diabetes usually have problem with obesity,polycystic ovary syndrome (PCOS) or acanthosis nigricans,etc.The diagnosis of children and adolescents with type 2 diabetes can through the clinical symptoms,fasting glucose,oral glucose tolerance test (OGTT),insulin autoantibodies and C-peptide levels.Compared with type 1 diabetes,children and adolescents with type 2 diabetes develop micro-vascular complications more easily and earlier.The treatment of children and adolescents with type 2 diabetes includes diabetic health education,diet control,exercise,oral drugs and insulin.
出处 《国际内分泌代谢杂志》 北大核心 2013年第6期402-405,共4页 International Journal of Endocrinology and Metabolism
关键词 2型糖尿病 儿童 青少年 诊断 治疗 Type 2 diabetes mellitus Children Adolescents Diagnosis Treatment
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  • 1王燕,吴利平,林琴,马勤香,王力.以家庭为中心儿童1型糖尿病个案管理照护方案的构建[J].中国护理管理,2020,0(1):145-150. 被引量:21
  • 2张昕,沈水仙,罗飞宏,支涤静,赵诸慧,陆忠,叶蓉,程若倩.上海市卢湾区青少年2型糖尿病患病率调查[J].中国循证儿科杂志,2006,1(3):204-209. 被引量:45
  • 3曹冰燕,米杰,巩纯秀,程红,颜纯,侯冬青,刘敏,桑艳梅,朱逞.北京市19593名儿童青少年糖尿病患病现况调查[J].中华流行病学杂志,2007,28(7):631-634. 被引量:29
  • 4Reynolds RM, Labad J, Sears AV, et al. Glucoeorticoid treatment and impaired mood, memory and metabolism in people with diabe- tes : The Edinburgh Type 2 Diabetes Study[ J]. Eur J Endoerinol, 2012,166(5 ) :861-868.
  • 5Revsin Y, Rekers NV, Louwe MC, et al. Glucocorticoid receptor blockade normalizes hippocampal alterations anti cognitive impair- ment in streptozotocin-induced type 1 diabetes mice[ J]. Nemnpsy- chopharmacology, 2009,34 ( 3 ) :747-758.
  • 6Trementino L, Appolloni G, Concettoni C, et al. Association of glueoeortieoid eeplor polymo3hism A3669G with decreased risk of deveh)ping diabetes in patients with Cushing s syndrome [ J ]. Eur J Endoerinol, 2012,166( 1 ) :35-42.
  • 7Mouton V, Toussaint L, Vertommen D, et al. Heart 6-phospho- fructo-2-kinase activation by insulin requires PKB ( protein kinase B), but not SGK3 (serum- and glucocorticoid-induced protein kinase 3 ) [ J ]. Biochem J, 2010,431 ( 2 ) :267-275.
  • 8Islam A, Chen Y, Poth M, et al. Glucocorticoid receptor density correlates with health risk factors and insulin sistance in Cauca- sian and African American subjects[ J]. Exp Clin Endocrinol Dia- betes, 2012,120( 8 ) :477-481.
  • 9De Paula FM, Boschero AC, Carneiro EM, et al. Insulin signaling proteins in pancreatic islets of insulin-resistant ztts induced by glu- cocorticoid[ J]. Biol Res, 2011,44( 3 ) :251-257.
  • 10Costa MM, Violato NM, Taboga SR, et al. Reduction of insulin sig- nalling pathway IRS-1/IRS-2/AKT/mTOR and decrease of epitheli-al cell proliferation in the prostate of glucocorticoid-treated rats[ J ]. Int J Exp Pathol, 2012,93 ( 3 ) : 188-195.

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