胃旁路术治疗2型糖尿病的研究进展

Gastric bypass surgery for the treatment of type 2 diabetes mellitus

全球糖尿病的发病率逐年上升,现有的规范化内科治疗仍不能完全阻止其病情进展及其并发症的发生,其治疗已成为世界性的难题.减重手术治疗2型糖尿病已在临床使用多年,其中应用最广泛的是胃旁路术,它可引起持久的体重减轻、缓解肥胖相关并发症,尤其是2型糖尿病.然而其治疗机制、适用人群、术后部分患者糖尿病复发的机制尚不明确,有待进一步研究阐明.

The prevelance of diabetes increased significantly year by year around the world,while medicine couldn＇t prevent its progression and develoment of complications.The treatment of diabetes had become a worldwide problem.Bariatric surgeries had been used to treat type 2 diabetes for many years,of which the nost frequently performed operation,gastric bypass,caused profound weight loss and ameliorated obesity-related comorbid conditions,especially type 2 diabetes mellitus.However,the therapeutic mechanism,targetpopulation and mechanism of recurrence of type 2 diabetes after gastric bypass surgery are not very clear.Further studies need to be performed to verify these problems.