人工硬脑膜在去大骨瓣减压术治疗重症颅脑损伤中的应用

The Application of Artificial Dura Mater to Hemicraniectomy in Patients with Severe Traumatic Brain Injury

目的:探讨大骨瓣结合人工硬脑膜修补术治疗重症颅脑损伤的临床效果。方法:回顾性分析本院自2010年1月-2013年6月收治的43例重症颅脑损伤患者的临床资料,总结手术经验,应用GOS预后评估法对患者术后1个月至半年效果进行评价。结果:1例患者因急性高颅压而死亡,余42例存活。术后1个月至半年内GOS评估:痊愈7例(16.2%),轻残12例(27.9%),中残15例(34.8%),重残5例(11.6%),植物状态3例(7.0%),死亡1例(2.3%)。其中40例存活者得到长期随访,无明显不良反应。结论:大骨瓣减压结合人工硬脑膜修补术治疗重症颅脑损伤疗效可靠,值得临床推广应用。

Objective： To explore the application of large trauma and artificial dural in traumatic brain injury surgery.Method： 43 patients with artificial dural in traumatic brain injury surgery were analysed retrospectively, from January 2010 to June 2013.Result： 1 patient died of acute high intracranial pressure, more than 42 cases of survival.Evaluation of 1 to six months after GOS： 7 cases（16.2%） were cured, mild disability in 12 cases（27.9%）, moderate disability in 15 cases（34.8%）, severe disability in 5 eases（11.6%）, 3 cases（7%） of vegetative state, 1 case（2.3%） was death.The 40 survivors were followed up, no obvious adverse reaction.Concluslon： Artificial dural repairingcom is safe and effective in large trauma brain injury surgery, It is worthy of clinieal application.