抗病毒药联合半导体激光治疗肋间神经胸段带状疱疹的疗效观察

Antiviral therapy combined semiconductor laser thoracic intercostal nerve efficacy of herpes zoster

目的探讨抗病毒药物联合半导体激光治疗肋间神经胸段带状疱疹的临床疗效。方法选择200例肋间神经胸段带状疱疹患者,治疗前根据疼痛量表评分均等分为常规治疗组和常规+激光对照组,常规治疗组给与常规抗病毒药物及营养神经药物治疗,常规+激光对照组在常规治疗的基础上加用半导体激光照射治疗。通过NRS疼痛评分、水疱干瘪、水疱结痂、结痂脱落>80%和平均住院日评价两组疗效。结果在排除部位不同、面积不同、年龄性别等可变因素干扰后,常规+激光组患者无论是主观指标(NRS疼痛评分)还是客观指标(水疱结痂、结痂脱落>80%和平均住院日)均明显优于常规治疗组,且差异均有统计学意义(P<0.05)。结论抗病毒药常规治疗联合半导体激光治疗带状疱疹疗效优于单纯抗病毒药常规治疗。

Objective To investigate curative effect in the treatment of thoracic intercostal nerve herpes zoster by using antiviral treatment combination with semiconductor laser ways. Methods Total 200 cases of thoracic intercostal nerves herpes zoster patients with ages from 20 to 70 years old were included into this study. Before the treatment, the cases were classified into conventional treatment group and the control group ac- cording to pain scale score rules. The patients of control group were treated with conventional ways combination with laser. Conventional treatment group received conventional antiviral drugs and neurotrophic drugs, while control group received both conventional treatment and the use of semi- conductor laser irradiation. The curative effect of two groups were evaluated by NRS pain scores, blisters dry, blisters scab, scab off more than 80% and the average days of stay in hospital. Results After exclusion of some confounding factors, the results showed that patients in the group that received both conventional treatment and the use of semiconductor laser irradiation was significantly better than conventional treatment group in plus NRS pain scores, blisters scab, indicators of scab off more than 80% and the average daily hospitalization. There were significant statistically differences between two groups. Conclusion Antiviral therapy method combined with semiconductor laser treatment of herpes zoster is better than conventional antiviral treatment.