500例骨科Ⅰ类切口手术围术期预防性应用抗菌药物调查分析

Analysis of perioperative prophylactic use of antibacterials in 500 cases of typeⅠincision surgery

目的：通过了解我院骨科Ⅰ类切口手术围术期预防性应用抗菌药物的使用情况，为规范抗菌药物合理应用提供依据。方法随机抽取2011年7月～2012年2月出院的500份Ⅰ类切口手术病历资料，进行统计、分析。结果抗菌药物预防应用率100％，抗菌药物使用以单一药物为主；抗菌药物使用频次排序列前3位的依次为头孢硫脒、头孢呋辛、头孢替安。抗菌药物选择合理的占62．0％，给药时机选择合理的占57．0％，术后用药疗程合理的占40．0％，用法用量合理的占79．4％。结论我院骨科Ⅰ类切口手术患者预防性使用抗菌药物存在用药品种选择不当、术前给药时机不够准确和术后用药时间较长等问题，有待进一步规范化管理。

Objective To investigate the utilization information of antibacterials in orthopedics department of our hospital in type Ⅰincision surgery ,and to provide references for rational use and management of antibacterials .Methods 500 cases of antibacterials application of typeⅠ incision surgery inpatients in our hospital from July 2011 to 2012 were summarized and analyzed ,retrospec-tively .Results The prophylactic use of antibacterials during perioperative period reached upto 100% .Antibacterials ,as a single a-gent-based ,was used in all cases ,and the ranking orders of usage frequency was cefathiamidine ,cefuroxime and cefotiam .The rea-sonable choice rate of antibacterials ,administration time ,postoperative medication regimen and administration dosage was 62.0% , 57 .0% ,40 .0% and 79 .4 % ,respectively .Conclusion The prophylactic antimicrobial use in type Ⅰ incision surgery still had un-reasonable phenomena in our hospital which need to be further standardized and managed .