温针灸配合盐酸氨基葡萄糖治疗膝骨关节炎临床研究

Clinical Study on Warm Needling plus Glucosamine Hydrochloride for Knee Osteoarthritis

目的观察温针灸配合盐酸氨基葡萄糖治疗膝骨关节炎的临床疗效。方法将90例膝骨关节炎患者随机分为温针组、药物组和针药组,每组30例。温针组采用温针灸治疗,药物组采用口服盐酸氨基葡萄糖治疗,针药组采用温针灸配合盐酸氨基葡萄糖治疗。比较3组治疗前后WOMAC膝部疼痛和膝部功能评分、患者满意度(PSS)、SF-36评分。结果 3组患者治疗6星期后膝部疼痛及膝部功能评分与同组治疗前比较,差异均具有统计学意义(P<0.05)。针药组患者治疗2星期、6星期后膝部疼痛及膝部功能评分与温针组和药物组比较,差异均具有统计学意义(P<0.05)。3组治疗6星期后PSS评分与同组治疗前比较,差异均具有统计学意义(P<0.05)。针药组患者治疗2星期、6星期后PSS评分与温针组和药物组比较,差异均具有统计学意义(P<0.05)。温针组治疗后躯体功能、躯体自觉功能、疼痛指数评分与同组治疗前比较,差异均具有统计学意义(P<0.05)。药物组治疗后躯体功能、躯体自觉功能、疼痛指数、精力、情绪角色功能、精神健康指数评分与同组治疗前比较,差异均具有统计学意义(P<0.05)。针药组治疗后躯体功能、躯体自觉功能、疼痛指数、总体健康感觉、社会功能、情绪角色功能评分与同组治疗前比较,差异均具有统计学意义(P<0.05)。结论温针灸配合盐酸氨基葡萄糖是一种治疗膝骨关节炎的有效方法。

Objective To observe the clinical efficacy of warm needling plus Glucosamine hydrochloride in treating knee osteoarthritis （KO）. Method Ninety KO patients were randomized into a warm needling group, a medication group, and an acupuncture-medication group, 30 in each. The warm needling group was intervened by warm needling treatment, the medication group was by oral administration of Glucosamine hydrochloride, and the acupuncture-medication group was by warm needling plus Glucosamine hydrochloride. WOMAC scores of knee pain and knee function, patient satisfaction score （PSS）, and SF-36 score were compared among the 3 groups before and after treatment. Result After 6-week treatments, the scores of knee pain and knee function were changed significantly in the three groups （P〈0.05）. The acupuncture-medication group was significantly different from the warm needling group and medication group in comparing the scores of knee pain and knee function respectively after 2-week and 6-week treatments （P〈0.05）. After 6-week treatments, the PSS scores were changed significantly in the three groups （P 〈0.05）. The acupuncture-medication group was significantly different from the warm needling group and medication group in comparing the PSS score respectively after 2-week and 6-week treatments （P〈0.05）. After treatment, the physical functioning score, physical role functioning score, and bodily pain score were changed significantly in the warm needling group （P〈0.05）. After treatment, the physical functioning score, physical role functioning score, bodily pain score, vitality score, emotional role functioning score, and mental health score were changed significantly in the medication group （P〈0.05）. After treatment, the physical functioning score, physical role functioning score, bodily pain score, general health perceptions score, social role functioning score, and emotional role functioning score were changed significantly in the acupuncture-medication group （P〈0.05）. Conclusion Warm needling plus Glucosamine hydrochloride is an effective approach in treating KO.