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微流控芯片技术在药物活性研究中的应用进展 被引量:6

Applications of microfluidic chip in drug activity research
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摘要 微流控芯片技术作为近年来最前沿的分析技术之一,具有微型化、高通量、高内涵、多功能集成等特点,在药物活性研究领域中得到广泛的关注。本文简单介绍了微流控芯片的原理和相关技术,从细胞、"器官"、模式生物3个层面综述微流控芯片技术在药物活性研究中的应用进展,并展望了微流控芯片的发展前景。 Microfluidic chip, which is one of the most striking analytical technologies in recent years, has many ben- efits including miniaturizing, high -throughput, high -content, and multi -functional intergration. It has received widespread attention in the field of drug activity research. This paper briefly introduced the general concept of mi- erofluidic chip and related technologies. The applications of microfluidic chips in drug activity research were re- viewed from aspects of cells, organs and organisms. At last, the development of microfluidic chips was prospected.
出处 《药物分析杂志》 CAS CSCD 北大核心 2013年第11期2013-2018,共6页 Chinese Journal of Pharmaceutical Analysis
基金 国家自然科学基金(No.81273472) 上海市科学技术委员会课题(No.12401900802)
关键词 微流控芯片技术 药物活性 细胞阵列芯片 “器官”芯片 模式生物芯片 秀丽隐杆线虫 microfluidic chip drug activity cellular microarrays organs on a chip whole organisms on a chip Cae- norhabditis elegans
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参考文献46

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同被引文献104

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