急性心肌梗死患者住院期间新发心房颤动的多因素分析

Risk Factors of New Onset Atrial Fibrillation in Patients with Acute Myocardial Infarction during Hospitalization

目的探讨影响急性心肌梗死后患者住院期间新发心房颤动（房颤）的影响因素方法收集2010年8月至2011年12月间心内科住院首次诊断为急性心肌梗死（ST段抬高或者非ST段抬高）患者共444例，根据心律情况分为窦性心律组391例和新发心房颤动组53例按照潜在危险因素收集数据，对影响心肌梗死后新发房颤的危险因素进行单因素和Logistit．多因素回归分析结果444例诊断为急性心肌梗死的患者中，新发心房颤动53例，Logistic多因素回归分析显示：年龄、Killip分级和β-受体阻滞剂的比值比（OR值）分别为1．653、10．728和0．317，95％CI分别为1．047～2．610、4．725～24．359和0．152～0．663结论年龄和心功能状况为影响急性心肌梗死后新发房颤的危险因素，而使用β-受体阻滞剂为保护因素。

Objective To study the risk fac＇tors of new-onset atrial fibrillation（AF） among patients with acute myoc, ardial intarctinn （ AMI ）during hospitalization.. Metheds From August 2010 to December 2011, a tntal of 444 patients with first-ever AMI （ ST segment elevation or non ST seg- ment elevation ） adnfitted to the First Hospital of China Medical University were selected. According to the incidence of AF, the subjects were divid- ed into sinus rhyhm group （n =391 ） and AF group （n =53）. Data were collected base on Ihe potential risk though. Logistic regression analyses of single factor and multiple fhctors were performed to evaluate the risk factors of new-onset AF among AMI patients. ResuRs A total of 444 cases were diagliosed ers A M1, of whom 53 cases of AF were observed. Logistic regression mlalysis showed that the odds ratio of age, Killip grade and use of beta-blocker were 1.653, 10.728 and 0.317, respectively （95% CI ： 1.047-2.610,4.725-24.359 and 0.152-0.663 ）. Conclusion Age and cardiac fhnction were the risk factors for new-onset atrial fibrillation after acute myocardial infarction, and the use of beta blocker was a proleetive tactor.