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宫颈胰岛素样生长因子结合蛋白-1联合宫颈超声测量预测早产的价值

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摘要 目的探讨宫颈胰岛素样生长因子结合蛋白-1联合宫颈超声测量预测早产的价值。方法符合入组条件的先兆早产孕妇84例,取膀胱结石位,常规消毒外阴、窥器暴露宫颈后取宫颈管内分泌物,测定宫颈胰岛素样生长因子结合蛋白-1(IGFBP-1)后再使用GE-E8型彩超经阴道测量宫颈结构,并计算出宫颈指数。结果 IGFBP-1阳性对早产预测的阳性率为65.0%,阴性预测率为89.1%;宫颈指数(<0.5)对早产预测的阳性率为85.0%,阴性预测率为96.7%;二者结合对早产预测的阳性率为90.0%,阴性预测率为90.5%。结论在选择宫颈指数≥0.8时,两者的联合检测对于早产预测的阳性率为90.0%,而阴性预测差异无统计学意义;在选择宫颈指数<0.5时,两者的联合检测阴性预测率为96.7%,差异有统计学意义,而阳性预测率差异无统计学意义。
出处 《海南医学》 CAS 2013年第21期3229-3231,共3页 Hainan Medical Journal
基金 深圳市宝安区科技计划--社会公益(医疗卫生类)立项项目(编号:20110451)
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参考文献12

  • 1乐杰.妇产科学[M].7版.北京:人民卫生出版社,2009:92-99.
  • 2路阳,苏赛,马春艺.经阴道超声检查宫颈结构在早产治疗中的应用价值[J].中外医疗,2011,30(12):176-176. 被引量:9
  • 3马京梅,杨慧霞,郭战坤,时春艳,张运平,马仲秋,范玲,周士平,杨孜,王珈略.阴道分泌物胎儿纤维连接蛋白与宫颈长度联合预测早产的多中心前瞻性研究[J].中华围产医学杂志,2009,12(3):190-193. 被引量:18
  • 4Luana Danti,Federico Prefumo,Andrea Lojacono,et al.The combi-nation of short cervical length and pMGFBP-1 in the prediction ofpreterm delivery in symptomatic women[J].Journal of Mater-nal-Fetal and Neonatal Medicine,2011,24(10):1262-1266.
  • 5American College of Obstetricians and Gynecologists.Committeeon Practice Bulletins-Obstetrics.ACOG practice bulletin no.127:Management of preterm labor[J].Obstet Gynecol,2012,119(6):1308-1317.
  • 6宿仕萍,袁幼红,吴嫒嫒,乔福元,余俊.联合筛查在预测早产中的应用研究[J].中国妇幼保健,2009,24(18):2490-2492. 被引量:8
  • 7Maia B,Ana IMH,Cristina CP,et al.Phosphorylated insulin-likegrowth factor binding protein-1 and cervical measurement in wom-en with threatening preterm birth[J].Acta Obstetricia et Gynecolog-ica,2010,89:268-274.
  • 8PAatemoster D,Riboni F,Vitulo A,et al.Phosphorylated insulin-likegrowth factor binding protein-1 in cervical secretions and sonograph-ic cervical length in the prediction of spontaneous preterm delivery[J].Ultrasound Obstet Gynecol,2009,34:437-440.
  • 9Cooper S,Lange I,Wood S,et al.Diagnostic accuracy of rapidphIGFBP-I assay for predicting preterm labor in symptomatic pa-tients[J].Journal of Perinatology,2012,32:460-465.
  • 10Francesca R,Anna V,Marinella D.Biochemical markers predictingpre-term delivery in symptomatic patients:phosphorylated insu-lin-like growth factor binding protein-1 and fetal fibronectin[J].Arch Gynecol Obsteti 2011,284:1325-1329.

二级参考文献35

  • 1时春艳,杨慧霞,金燕志,杨孜,郭艳军,谢毅,徐先明,董悦.胎儿纤维连接蛋白对先兆早产孕妇发生早产的预测价值[J].中华围产医学杂志,2006,9(1):2-5. 被引量:70
  • 2崔艳萍.宫颈分泌物中胰岛素样生长因子结合蛋白-1预测早产的价值[J].国际医药卫生导报,2006,12(4):20-21. 被引量:2
  • 3Lockwood CJ,Senyei AE,Dische MR,et al.Fetal fibronectin in cervical and vaginal secretions as a predictor of preterm delivery.N Engl J Med 1991,325:669-674.
  • 4Iams JD.Prediction and early detection of preterm labor.Obstet Gynecol,2003,101,402-412.
  • 5American College of Obstetricians and Gynecologists.ACOG Practice Bulletin,Assessment of risk factors for preterm birth.Clinical management guidelines for obstetrician-gynecologists.Number 31,October 2001.Obstet Gynecol,2001,31:709-713.
  • 6Leitich H,Kaider A.Fetal fibronectin-how useful is it in the prediction of preterm birth? BJOG 2003,110(Suppl 20):66-70.
  • 7Giles W,Bisits A,Knox M,et al.The effect of fetal fibronectin testing on admissions to a tertiary maternal-fetal medicine unit and cost savings.Am J Obstet Gynecol,2000,182:439-442.
  • 8Asakura H,Fukami T,Kurashina R,et al.Significance of cervical gland area in predicting preterm birth for patients with threatened preterm delivery:comparison with cervical Length and fetal fibronectin.Gynecol Obstet Invest,2009,68:1-8
  • 9Kiefer DG,Vintzileos AM.The utility of fetal fibronectin in the prediction and prevention of spontaneous preterm birth,Rev Obstet Gynecol,2008,1:106-112.
  • 10Gomez R,Romero R,Medina L,et al.Cervicovaginal fibronectin improves the prediction of preterm delivery based on sonographic cervical length in patients with preterm uterine contractions and intact membranes.Am J Obstet Gynecol,2005,192:350-359.

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