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肿瘤标记物与前列腺癌的早期诊断

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摘要 目前最常用的筛选前列腺癌的肿瘤标记物是前列腺特异性抗原(PSA),但PSA特异性及对前列腺癌的早期诊断价值仍然存在争议,因此大量研究转向寻找新的前列腺癌标志物,已取得不少成果。目前认为前列腺癌抗原3基因、α-甲基酰基辅酶A消旋酶、TMPRSS2-ERG融合基因和微精原蛋白-β等肿瘤标记物对前列腺癌的早期诊断有较高的临床意义。本文将对前列腺特异性抗原(PSA)及其亚型、尿液中的生物学标记物(前列腺癌抗原3基因,α-甲基酰基辅酶A消旋酶,TMPRSS2-ERG融合基因和微精原蛋白-β)和其他新型的血清和尿液中的标志物研究现状作简要概述。
作者 郑伟 覃展偶
机构地区 桂林医学院附属医院泌尿外科
出处 《海南医学》 CAS 2013年第22期3351-3353,共3页 Hainan Medical Journal
关键词 肿瘤标记物 前列腺癌 早期诊断
分类号 R737.25 [医药卫生—肿瘤]
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参考文献23

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二级参考文献37

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海南医学
2013年 第22期

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