摘要
目的探讨晚期鼻咽癌患者对EB病毒晚期潜伏膜蛋白(EBV-LMP)的特异性细胞免疫应答问题。方法提取鼻咽癌患者自体单个核细胞体外培养,加入EBV-LMP2抗原制成致敏淋巴细胞,致敏淋巴细胞经患者皮内注射,观察其细胞免疫指标水平的变化。结果经致敏淋巴细胞注射后的鼻咽癌患者其EB病毒特异性细胞免疫水平随注射次数的增加而明显增高。结论鼻咽癌患者特异性细胞免疫治疗可作为鼻咽癌治疗的有效辅助手段。
Objective To probe into specific cellular immunity to EBV-LMP in advanced nasopharyngeal carcinoma patients .Methods Peripheral blood mononuclear cell drawn from nasopharyngeal carcinoma patients were cultured in vitro.EBV-LMP2 was added to prepare sensitized lymphocytes cells , which was injected into patients . Change in specific cellular immunity level was observed .Results With sensitized lymphocytes cell injected specific cellular immunity level increased in nasopharyngeal carcinoma patients .Conclusion Specific cellular immunity cure can be effective adjuvant therapy to the nasopharyngeal carcinoma patients .
出处
《中国临床新医学》
2013年第11期1041-1043,共3页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
基金
广西科学研究与技术开发计划项目(编号:桂科自9632023)
关键词
鼻咽癌
特异性细胞免疫
Nasopharyngeal carcinoma
Specific cellular immunity
