女性2型糖尿病患者无症状菌尿致病菌及其药敏结果分析

The pathogenic bacteria from asymptomatic bacteriuria and its drug sensitivity analysis for female patients with type 2 diabetic mellitus

目的：分析女性2型糖尿病（T2DM）无症状菌尿（ASB）培养和药敏试验结果，指导临床应用抗菌素。方法对2010-06～2011-12住院的324例女性T2DM伴ASB患者尿培养和药敏试验结果进行回顾性分析。结果本组培养阳性率为65.7％，其中G-杆菌占60.7％，G＋球菌占34.6％，念珠菌属占4.7％。 G-杆菌中大肠埃希菌、变形杆菌居多，对氨苄西林、环丙沙星及复方新诺明普遍耐药，对第三代头孢菌素敏感。G＋球菌中以肠球菌属多见，对大多数药物不敏感，对万古霉素极少耐药。结论女性T2 DM伴ASB患者致病菌以大肠埃希菌、肠球菌多见，对多数常用的抗生素不敏感，应根据药敏试验结果指导用药。

Objective To analyze the results of urine culture and drug sensitivity test of asymptomatic bacte-riuria（ASB） pathogenic bacteria for female patients with type 2 diabetes mellitus （T2DM）, and guide clinical the use of antibiotics .Methods Retrospective analysis on the results of urine culture and drug sensitivity test for hospi -talized female patients with T2DM associated with ASB was performed from June 2010 to December 2011.Results The positive rate of urine culture was 65.7%, of which G -bacilli accounted for 60.7%, G＋cocci accounts for 34.6%, candida accounts for 4.7%.Most G-Bacillus were escherichia and coli ,proteus, which had drug resistance to ampicillin, ciprofloxacin and compound nuomingduo , and sensitive to third generation cephalosporin .G＋cocci, most of which were enterococcus were insensitive to most drugs and were very little resistant to vancomycin .Conclu-sion For female patients with T2DM associated with ASB, it is common to see Escherichia coli and Enterococcus in Pathogenic bacteria , which is insensitive to most commonly used antibiotics .Drug use should be guided by the results of drug sensitivity test .