血清β_2-m和SF在非霍奇金淋巴瘤诊治中的应用价值

The Applicative Value of Serum β_2-m and Ferritin in Diagnosis and Treatment of non-Hodgkin Lymphoma

目的:探讨血清β2微球蛋白(β2-m)、铁蛋白(SF)在非霍奇金淋巴瘤(NHL)诊治中的作用。方法:收集64例NHL患者的血清,采用免疫发光法荧光偏振免疫检测(FPIA)技术测定血清β2-m,采用化学发光免疫分析技术测定SF。结果:NHL患者血清β2-m、SF的升高与临床分期、化疗效果有关。结论:血清β2-m和SF可作为NHL患者临床诊断、化疗效果的辅助指标。

Objective To explore the significance of serum β2 microglobulin （β2-m） and serum ferritin （SF） in diagnosis and treatment of non-Hodskln lymphoma. Methods Serum was collected from 64 cases of patients with NHL, the serum β2-m was determined by fluorescence polarization immmloassay（FPIA） and the SF was measured by electrochemical immlmoassay chemiluminescence method. Results Elevation of the NHL patients＇ serum β2-m and SF showed closely related to clinical stages and effect of chemotherapy. Conclusion The serum β2-m and SF can be used as the auxiliary indexes for NHL patients＇ clinical diagnosis and chemotherapeutic effect.