抗菌药物专项整治活动对抗菌药物使用影响分析

Analysis of the impact of Special Rectification Activities on Clinical Use of Antibacterials

目的对比2010年下半年和2011年下半年卫生部抗菌药物专项整治活动前后抗菌药物的使用情况,探索政策实施对抗菌药物使用的影响。方法从《医院处方分析合作项目》中收集2009-2011年我国6所城市75家医院的电子处方,采用Excel对各项处方数据进行汇总,对用药频度(DDDs)、用药金额等进行统计。结果抗菌药物专项整治活动降低了抗菌药物的用药金额、DDDs值,但是除抗菌药物之外的其他药物用药金额显著上升,抗菌药物的处方比例在一些抗菌药物常用科室未降反升,如发热科,这在一定程度上反映了医院"总量控制,结构调整"的应对策略。结论卫生部抗菌药物专项整治活动对抗菌药物的滥用起到很大的遏制作用,使抗菌药物处方量和总金额双双下降,但其他药物用药金额出现上升趋势。

OBJECTIVE To investigate the influence of MOHC （ Ministry of Health of The PRC） special rectification activities of antibacterials on clinical use of antibacterials in China. METHODS The original electronic prescriptions including antibiotics were collected from 79 comprehensive hospitals in 6 cities between 2009 and 2011 from the Hospital Prescription Analysis Programs. Excel software was used to summarize all the prescription data and calculate antibiotics DDDs, cost, etc. RESULTS The implementation of the activities reduced the cost and DDDs of antimicrobial agents, but the proportion of antibiotics prescriptions didn＇t drop in the key departments. CONCLUSION The implementation of specia~ rectification activities of antibacterials of MOHC has produced a great influence on the use of antimicrobials, as shown by a decline of the total cost and prescription number of antimicrobials, but the cost of other medicines showed a rising trend.