摘要
以脏器指数、迟发性变态反应、脾淋巴细胞增殖反应、抗体生成细胞及巨噬细胞吞噬指数等为检测指标,研究豆渣RNA和豆渣RNA酶解物对小鼠的细胞免疫、体液免疫及非特异性免疫功能的影响,并比较二者免疫调节作用的差异。结果表明,豆渣RNA及其酶解物均能显著增加小鼠脾脏重量,促进脾淋巴细胞增殖能力,提高抗体生成细胞水平,说明豆渣RNA及其酶解物可通过促进机体的细胞免疫和体液免疫而发挥免疫调节作用。其中,豆渣RNA酶解物高剂量组(10.0mg/mL)的效果明显优于豆渣RNA组。
Organ index, delayed allergy reaction, spleen lymphocyte transformation, antibody generation cell and phagocytic count of macrophage cell were used to evaluate the effects of okara RNA and its hydrolysates on the cellular immunity, humeral immunity and nonspecific immunity function. And immunomodulatory effects were compared between okara RNA and its hydrolysates.The results showed that okara RNA and its hydrolysates could remarkably increase the mice spleen weight, promote spleen lymphocyte proliferation and improve the level of antibody formation cell, which suggest that okara RNA and its hydrolysates might modulate immune ruction by promoting the cellular immune and humoral immunity.Among them,immunomodulatory effects of high doses group of okara RNA hydrolysates（10mg/mL） was better than that of okara RNA group.
出处
《食品工业科技》
CAS
CSCD
北大核心
2013年第23期332-335,共4页
Science and Technology of Food Industry
基金
黑龙江省博士后科研启动基金(LBH-Q10152)
