氧驱动雾化吸入与空气压缩泵雾化吸入治疗小儿哮喘的临床效果比较

Comparision of clinical curative effect oxygen-driven aerosol's and air compressor pump atomizing inhalation's on treatment of infantile asthma

目的对比氧驱动与空气压缩泵雾化吸入治疗小儿哮喘的临床效果,探究治疗小儿哮喘的最有效雾化吸入方法。方法将2012年2月—2013年2月南京军区福州总医院第一附属医院儿科收治的89例急性支气管哮喘发作的患儿随机分为两组,对照组45例,以空气压缩泵为动力进行雾化吸入药物(复方异丙托溴铵溶液联合布地奈德混悬液)治疗,观察组44例,以氧驱动雾化吸入药物(同对照组)治疗,对比两组患儿治疗前后血氧饱和度,治疗3日后评价两组治疗效果。结果观察组在治疗后血氧饱和度的改善显著,P<0.05,差异有统计学意义,对照组患儿雾化吸入前后血氧饱和度并无明显变化;治疗3天后评估治疗效果,观察组总有效率(95.45%)高于对照组(75.56%),P<0.05,有统计学意义。结论相同药物治疗下,以氧驱动为动力吸入药物治疗小儿哮喘的有效性高于空气压缩泵,且副作用小,患儿接受度高。

Objective To compare oxygen driven aerosol＇ s and air compressor pump atomizing inhalation＇ s clinical curative effect on the treatment of infantile asthma, to discuss the most efficient aerosol inhalation method for infantile asthma. Methods Chose 89 eases of these acute bronchial asthma infantile patients who have been admitted at paediat tics department of our hospital from February 2012 to February 2013, divided them into observation group and control group randomly, gave air compressor pump atomizing inhalation （compound isopropyl bromide solution combined with budesonide suspension） to these 45 cases of patients incontrol group as treatment, while gave oxygen driven aerosol （compound isopropyl bromide solution combined with budesonide suspension） to these 44 cases of patients in observa tion group, compared these two groups＇ infantile patients ＇ oxyhemoglobin saturation before and later treatment, and eval uated their treatmnt effects after 3 days of treatment. Results After treatment, observation group＇ s infantile patients＇ oxyhemoglobin saturation improved obviously, P 〈 0. 05, it has statistics meaning, and control group＇ s patients＇ oxyhemo globin saturation did not have evident changes ;The evaluation result after three days of treatment showed that observation group ＇ s overall effective rate was 95.45%, it was higher than control group＇ s （ 75.56% ）, P 〈 0. 05, it has sttaistics meaning. Conclusions Under the same drug therapy, oxygen driven aerosol＇ s effectiveness is higher than air com pressor pump atomizing inhalation＇ s, and its side effect is fewer,infantile patients can accept it easily.