颈动脉粥样硬化与冠心病的相关性

Correlation between Carotid Atherosclerosis and Coronary Heart Disease

目的 :应用超声检查冠心病患者颈动脉粥样硬化程度,判断其与冠状动脉粥样硬化的相关性,探讨其对冠心病的预测价值。方法 :选择疑似冠心病、行冠脉造影的住院患者106例,根据冠状动脉造影结果分为:对照组(0支病变组),单只病变组,双支病变组,多只病变组。超声测量颈动脉IMT,同时注意观察动脉硬化斑块的大小、位置、数量及斑块性质等。结果 :颈动脉IMT值、颈动脉粥样硬化斑块积分各组间均有显著性差异,冠心病组明显高于对照组,多支病变组高于单支病变组。冠状动脉积分与颈动脉IMT值及冠状动脉积分与颈动脉硬化积分之间均呈显著性相关。结论 :颈部动脉血管的IMT及斑块对动脉粥样硬化有很好的预测价值,可作为预测冠状动脉粥样硬化的重要指标。

Objective ： Using the ultrasound to examine the degree of carotid atheroselerosis in patients with coronary heart disease, and to determine its correlation with coronary atherosderosis and its predictive value for coronary heart disease （ CHD ）. Methods ： 106 cases of hospitalized patients suspected coronary heart disease with coronary angiography were selected, and according to the results of coronary angiography were divided into four groups ： control group, single lesion group, double lesions group and multiple lesions group. Application of ultrasound was used to measure the IMT in carotid artery bifurcation and internal carotid artery, at the same time to observe atherosclerosis plaque size, location, quantity, and the nature of the plaque, etc. Results： Carotid artery IMT values and carotid artery atherosclerosis plaque integral were significantly different among groups. The multivessel lesions group was higher than single lesion group. Integral and carotid artery bifurcation coronary artery IMT values had negatively significant correlation. Conclusions ： Carotid artery IMT and plaque of atheroselerosis have good predictive value, and can be used as important predictors of coronary atherosclerosis.