曲美他嗪治疗不稳定心绞痛的疗效评价

Trimetazidine Evaluate the Efficacy of the Treatment of Unstable Angina

目的探讨不稳定心绞痛采用曲美他嗪进行临床治疗的效果。方法随机选取我院2010年-2012年收治的50例不稳定型心绞痛患者，分成对照组与观察组，对照组通过常规方法进行治疗，观察组在对照组治疗基础上添加曲美他嗪进行治疗，患者在治疗过程中出现心绞痛发作的则采用硝酸甘油片剂治疗，对患者的硝酸甘油消耗量、心绞痛发作频率进行记录。结果观察组患者硝酸甘油消耗量、心绞痛发作频率明显少于对照组；心电图改善情况明显优于对照组，两组数据对比具有统计学差异（P〈0．05）。结论不稳定型心绞痛患者通过曲美他嗪与常规方式相互结合治疗能够明显提高治疗效果，且没有严重不良反应，具有极大的应用价值。

Objective To study the unstable angina pectoris using the effect of trimetazidine for clinical treatment. Methods Randomly selected from our hospital in 2010 - 2012 were 50 patients with unstable angina, were divided into control group and observation group, control group treated by conventional method, the observation group was treated in the control group on the basis of added trimetazidine treatment, patients in the treatment of angina pectoris attack appeared in the process of using nitroglycerin tablet treatment, the patient of nitroglycerin consumption, frequency of angina pectofis attack. Results The observation group of patients with nitroglycerin consumption, frequency of angina pectoris attack less than control group obviously; Electrocardiogram improvement was better than control group, compared two groups of data with statistical difference （P〈0.05）.Conclusion The patients with unstable angina treated by trimetazidine mutual combination of conventional way can significantly improve the treatment effect, and no serious adverse reaction, it has great application value.