120例上消化道出血患者临床分析

Clinical analysis of 120 patients with gastrointestinal bleeding

目的探讨奥美拉唑静脉注射治疗消化性溃疡引起的上消化道出血临床效果。方法选取本院近年来收治消化性溃疡引起上消化道出血患者120例,采用随机数字表法分为对照组和观察组,其中对照组患者60例,采用常规上消化道出血内科治疗;观察组患者在对照组治疗基础上,加用奥美拉唑静脉滴注治疗;比较两组患者临床改善总有效率及止血率等。结果观察组患者临床治疗总有效率明显高于对照组,组间比较差异有统计学意义P<0.05);同时观察组患者止血率明显高于对照组,组间比较差异有统计学意义(P<0.05)。结论奥美拉唑静脉滴注用于消化性溃疡引起的上消化道出血可有效改善临床症状,提高止血效果。

Objective To investigate the therapeutic effect of omeprazole injection in treatment of gastrointestinal bleeding from peptic ulcer. Methods 120 patients with gastrointestinal bleeding from peptic ulcer were chose in recent years in our hospital and randomly divided into two groups including control group （60 patients） with general medical treatment of upper gastrointestinal bleeding from peptic ulcer and observation group （60 patients） with omeprazole injection on the basis of control group treatment; and the clinical treatment efficiency and the hemostatic rate of both groups were compared. Results The clinical treatment efficiency of observation group were significantly higher than control group（P〈0.05）. And the hemostatic rate of observation group weresignificantly higher than control group（P〈O.05）. Conclusion Omeprazole injection in treatment of gastrointestinal bleeding from peptic ulcer can efficiently improve clinical symptoms and the effects of hemostasis.